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XMT 1001

Known as: MER-1001, XMT1001, Polymeric Camptothecin Prodrug XMT-1001 
A polymeric prodrug of camptothecin (CPT) with potential antineoplastic activity. Polymeric camptothecin prodrug XMT-1001 consists of CPT conjugated… 
National Institutes of Health

Related topics

Related topics

3 relations

Broader (2)

CamptothecinPolymers
analogs & derivatives

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
A phase I study of the safety and pharmacokinetics (PK) of XMT-1001 given as an intravenous (IV) infusion once every three weeks to patients with advanced solid tumors
2574 Background: XMT-1001 is a water soluble macromolecular conjugate of camptothecin (CPT). In this novel CPT pro- drug, CPT is… 
2012
2012
Pharmacokinetics and Antitumor Efficacy of XMT-1001, a Novel, Polymeric Topoisomerase I Inhibitor, in Mice Bearing HT-29 Human Colon Carcinoma Xenografts
Purpose: To evaluate the pharmacokinetics and tissue disposition of macromolecular camptothecin (CPT) drug conjugate, XMT-1001… 
2010
2010
570 Phase 1 study of XMT-1001, a novel water soluble camptothecin conjugate, given as an IV infusion every 3 weeks to patients with advanced solid tumors
2010
2010
Abstract 3696: Pharmacokinetics (PK) of XMT-1001, a novel polymeric prodrug of camptothecin, in mice bearing HT-29 human colon carcinoma xenografts
Proceedings: AACR 101st Annual Meeting 2010‐‐ Apr 17‐21, 2010; Washington, DC Introduction: XMT-1001 is a water soluble… 
2009
2009
A phase I study of the safety and pharmacokinetics (PK) of XMT-1001 given as an intravenous (IV) infusion once every three weeks to patients with advanced solid tumors.
2574 Background: XMT-1001 is a water soluble macromolecular conjugate of camptothecin (CPT). In this novel CPT pro- drug, CPT is… 
2008
2008
Image Inpainting using Two-View Epipolar Geometry
We take a fresh look at the problem of removing occluders in an image using inpainting. We examine a geometric method that… 
2007
2007
A phase I study of the safety, tolerability, and pharmacokinetics of intravenous XMT-1001 in patients with advanced solid tumors.
A146 XMT-1001 is a water soluble macromolecular conjugate of camptothecin (CPT). In this novel CPT pro-drug, CPT is conjugated… 
2007
2007
MER-1001, a novel polymeric prodrug of camptothecin, is a potent inhibitor of LS174 and A2780 human tumor xenografts in a mouse model
781 Background and Rationale: MER-1001 is a polymeric prodrug derivative of camptothecin (CPT) in which CPT is chemically… 
2003
2003
MPEG-4 시스템에서 XMT-A의 VRML 변환
2002
2002
XMT-A를 이용한 MPEG-4 컨텐츠 저작
다양한 형태의 차세대 오디오/비디오 서비스를 위한 멀티미디어 데이터를 유연성 있게 부호화하기 위한 국제 표준 규격인 MPEG-4에서는 저작된 멀티미디어 컨텐츠를 저장하기 위한 포맷으로 XMT (eXtensible MPEG-4… 
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