Semantic Scholar uses AI to extract papers important to this topic.
Until the 1990s, cytotoxic chemotherapy has been the cornerstone of medical therapy for gastrointestinal (GI) cancers. Better… Expand OBJECTIVE
To investigate the drug targets related to Notch signaling pathway for glioma treatment.
Gene expression… Expand B237 Background: Ligand-independent activation of KIT is a critical factor in gastrointestinal stromal tumor (GIST) pathogenesis… Expand B69 Background: XL820 is a small molecule inhibitor of several receptor tyrosine kinases (RTKs) with growth-promoting and… Expand Exelixis is reaping the benefits of a licensing and development deal with GlaxoSmithKline that gives the pharma partner an option… Expand KINASE INHIBITOR, XL820, ADMINISTERED ORALLY TO PATIENTS WITH SOLID TUMORS Kyriakos P. Papadopoulos, Jordi Rodon, Alain Mita… Expand