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X Chromosome Inactivation function

Known as: Chromosome Inactivation, X, X Inactivation, Inactivation, X 
A human early embryonic event in which in any given cell one of a female's two X chromosomes becomes inactivated and converted into a Barr body… 
National Institutes of Health

Related topics

Related topics

9 relations
Lyon HypothesisX ChromosomeXIC geneaspects of radiation effects

Narrower (2)

X INACTIVATION, FAMILIAL SKEWED, 1 (disorder)X Inactivation, Familial Skewed, 2

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2006
Highly Cited
2006
Patients with Chronic Granulomatous Disease Have a Reduced Peripheral Blood Memory B Cell Compartment1
In this study, we have identified an altered B cell compartment in patients with chronic granulomatous disease (CGD), a disorder… 
Highly Cited
2002
Highly Cited
2002
High frequency of skewed X inactivation in young breast cancer patients
Introduction: Patients with invasive ovarian cancer were recently shown to have a higher frequency of skewed X chromosome… 
Review
2001
Review
2001
Imprinted X inactivation in eutherians: a model of gametic execution and zygotic relaxation.
Highly Cited
1998
Highly Cited
1998
Stabilization and Localization of Xist RNA are Controlled by Separate Mechanisms and are Not Sufficient for X Inactivation
These studies address whether XIST RNA is properly localized to the X chromosome in somatic cells where human XIST expression is… 
Highly Cited
1997
Highly Cited
1997
A variable domain of delayed replication in FRAXA fragile X chromosomes: X inactivation-like spread of late replication.
The timing of DNA replication in the Xq27 portion of the human X chromosome was studied in cells derived from normal and fragile… 
Highly Cited
1992
Highly Cited
1992
Maximum-likelihood analysis of human T-cell X chromosome inactivation patterns: normal women versus carriers of X-linked severe combined immunodeficiency.
Lymphocytes of female carriers of X-linked severe combined immunodeficiency (XSCID; McKusick 300400; HGM genetic locus… 
Highly Cited
1992
Highly Cited
1992
Different patterns of X inactivation in MZ twins discordant for red-green color-vision deficiency.
Two female identical twins who were clinically normal were obligatory heterozygotes for X-linked deuteranomaly associated with a… 
Highly Cited
1990
Highly Cited
1990
X chromosome inactivation of the human TIMP gene.
X chromosome inactivation results in the cis-limited inactivation of most, but not all, genes on one of the two X chromosomes in… 
Highly Cited
1987
Highly Cited
1987
Cytogenetic and molecular studies on a recombinant human X chromosome: implications for the spreading of X chromosome inactivation.
A pericentric inversion of a human X chromosome and a recombinant X chromosome [rec(X)] derived from crossing-over within the… 
Highly Cited
1984
Highly Cited
1984
Random X inactivation resulting in mosaic nullisomy of region Xp21.1----p21.3 associated with heterozygosity for ornithine transcarbamylase deficiency and for chronic granulomatous disease.
A young woman with normal gonadal development and mild mental retardation was found to have a small de novo interstitial deletion… 
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