X (Inactive)-Specific Transcript

Known as: NCRNA00001, Non-Protein Coding RNA 1, XIST 
 
National Institutes of Health

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3 relations
Homo sapiensXIST geneXIST wt Allele

Papers overview

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Highly Cited
2016
Highly Cited
2016
m6A RNA methylation promotes XIST-mediated transcriptional repression
The long non-coding RNA X-inactive specific transcript (XIST) mediates the transcriptional silencing of genes on the X chromosome… (More)
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2016
2016
Long non-coding RNA XIST regulates gastric cancer progression by acting as a molecular sponge of miR-101 to modulate EZH2 expression
BACKGROUND Long non-coding RNAs (lncRNAs) have emerged as critical regulators of tumor progression. However, the role and… (More)
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Highly Cited
2015
Highly Cited
2015
Knockdown of long non-coding RNA XIST exerts tumor-suppressive functions in human glioblastoma stem cells by up-regulating miR-152.
Glioblastoma (GBM) is the most common and aggressive primary brain tumor. Great interest persists in useful therapeutic targets… (More)
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2015
2015
Combined identification of long non-coding RNA XIST and HIF1A-AS1 in serum as an effective screening for non-small cell lung cancer.
OBJECTIVE Long non-coding RNAs (lncRNAs) XIST and HIF1A-AS1 have been shown to play important regulatory roles in cancer biology… (More)
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2009
2009
Misbehaviour of XIST RNA in Breast Cancer Cells
A role of X chromosome inactivation process in the development of breast cancer have been suggested. In particular, the… (More)
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Highly Cited
2002
Highly Cited
2002
BRCA1 Supports XIST RNA Concentration on the Inactive X Chromosome
BRCA1, a breast and ovarian tumor suppressor, colocalizes with markers of the inactive X chromosome (Xi) on Xi in female somatic… (More)
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Highly Cited
2002
Highly Cited
2002
Relationship of XIST expression and responses of ovarian cancer to chemotherapy.
Expression profiling to characterize cancer pharmacology has become a new approach to discover novel molecular targets for… (More)
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2002
2002
Unbalanced X;autosome translocations provide evidence for sequence specificity in the association of XIST RNA with chromatin.
Whether XIST RNA is indifferent to the sequence content of the chromosome is fundamental to understanding its mechanism of… (More)
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1997
1997
X inactivation in human testicular tumors. XIST expression and androgen receptor methylation status.
In female mammalian cells, inactivation of one of the X chromosomes compensates the increased dosage of X-linked genes as… (More)
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Highly Cited
1992
Highly Cited
1992
The human XIST gene: analysis of a 17 kb inactive X-specific RNA that contains conserved repeats and is highly localized within the nucleus.
X chromosome inactivation in mammalian females results in the cis-limited transcriptional inactivity of most of the genes on one… (More)
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