FAQ

Wy 26703

Known as: 1-Butanesulfonamide, N-(1,3,4,6,7,11b-hexahydro-2H-benzo(a)quinolizin-2-yl)-N-methyl-, monohydrochloride, trans-, Wy-26703 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1984-1988
012319841988

Related topics

Related topics

1 relation

Broader (1)

Quinolizines

Related mentions per year

Related mentions per year

1953-2018
1960198020002020
Wy 26703
Quinolizines

Papers overview

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1989
1989
5-HT1-like receptors requiring functional cyclo-oxygenase and 5-HT2 receptors independent of cyclo-oxygenase mediate contraction of the human umbilical artery.
1. The interactions between 5-hydroxytryptamine (5-HT) and the antagonists ketanserin, methysergide and phentolamine were studied… (More)
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1988
1988
Pharmacological analysis of postjunctional alpha-adrenoceptors mediating contractions to (-)-noradrenaline in the rabbit isolated lateral saphenous vein can be explained by interacting responses to…
1. The pharmacological characteristics of the alpha-adrenoceptor population in the rabbit isolated saphenous vein has been… (More)
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1988
1988
Evidence that the population of postjunctional-adrenoceptors mediating contraction of smooth muscle in the rabbit isolated ear vein is predominantly alpha 2.
1. Noradrenaline (NA), phenylephrine and UK-14304 elicited concentration-dependent contractions of the rabbit isolated ear vein… (More)
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1987
1987
Difference in the potency of alpha 2-adrenoceptor agonists and antagonists between the pithed rabbit and rat.
The subtypes of alpha-adrenoceptors which mediate pressor responses to sympathomimetic agonists or to nerve stimulation in pithed… (More)
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1987
1987
The effects of some α-adrenoceptor antagonists on the responses of the canine saphenous vein to B-HT 933, UK-14304 and methoxamine
The benzoquinolizines Wy 25309, Wy 26703 and Wy 27127, previously reported as potent antagonists at presynaptic α2-adrenoceptors… (More)
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1986
1986
Further characterization of the presynaptic alpha-1 receptor modulating [3H]ACh release from rat atria.
We have reported previously that norepinephrine (NE) and epinephrine reduce acetylcholine (ACh) overflow from superfused rat… (More)
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1985
1985
Studies of alpha 2-adrenoceptor antagonist potency in vitro: comparisons in tissues from rats, rabbits, dogs and humans.
The potencies of a number of selective alpha 2-adrenoceptor antagonists have been measured in preparations from four species. In… (More)
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1984
1984
Alpha2-adrenoceptor antagonism and other pharmacological antagonist properties of some substituted benzoquinolizines and yohimbine in vitro
Comparison of pA2 values for antagonism of clonidine induced inhibition of the electrically evoked contraction of the rat… (More)
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1984
1984
Affinity of WY 26703 for central and peripheral alpha 1- and alpha 2-adrenoreceptors in the rat; comparison with yohimbine.
The antagonist activity of Wy 26703 at vascular postjunctional alpha-adrenoreceptors was quantified against the methoxamine and B… (More)
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1984
1984
An investigation into the selectivity of a novel series of benzoquinolizines for alpha 2-adrenoceptors in vivo.
The potencies and selectivities of a novel series of benzoquinolizines for the alpha 2-adrenoceptor have been investigated in the… (More)
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