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Withanolide A

National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
Exploring neuroprotective potential of Withania somnifera phytochemicals by inhibition of GluN2B-containing NMDA receptors: An in silico study.
2016
2016
Silencing of sterol glycosyltransferases modulates the withanolide biosynthesis and leads to compromised basal immunity of Withania somnifera
Sterol glycosyltransferases (SGTs) catalyse transfer of glycon moiety to sterols and their related compounds to produce diverse… 
Highly Cited
2014
Highly Cited
2014
Withanolide A Prevents Neurodegeneration by Modulating Hippocampal Glutathione Biosynthesis during Hypoxia
Withania somnifera root extract has been used traditionally in ayurvedic system of medicine as a memory enhancer. Present study… 
2012
2012
Oxidative Stress Induced NMDA Receptor Alteration Leads to Spatial Memory Deficits in Temporal Lobe Epilepsy: Ameliorative Effects of Withania somnifera and Withanolide A
In the present study we investigate the effect of Withania somnifera (WS) root extract and Withanolide A (WA) in restoring… 
2012
2012
Carbohydrate and elicitor enhanced withanolide (withaferin A and withanolide A) accumulation in hairy root cultures of Withania somnifera (L.).
Leaves of Withania somnifera contained more withaferin A and withanolide A than roots indicating that these compounds mainly… 
Highly Cited
2011
Highly Cited
2011
The effect of polyamines on the efficiency of multiplication and rooting of Withania somnifera (L.) Dunal and content of some withanolides in obtained plants
An efficient mass multiplication protocol was developed for Withania somnifera (L.) Dunal from nodal explants of field-grown… 
Highly Cited
2010
Highly Cited
2010
Withanolide A and asiatic acid modulate multiple targets associated with amyloid-beta precursor protein processing and amyloid-beta protein clearance.
Alzheimer's disease (AD) is a progressive, neurodegenerative disease histochemically characterized by extracellular deposits of… 
Highly Cited
2010
Highly Cited
2010
Effects of macroelements and nitrogen source on biomass accumulation and withanolide-A production from cell suspension cultures of Withania somnifera (L.) Dunal
Withania somnifera is an important medicinal plant that contains withanolides and withaferins, both bioactive compounds. We have… 
Highly Cited
2007
Highly Cited
2007
Withanolide A biogeneration in in vitro shoot cultures of ashwagandha (Withania somnifera DUNAL), a main medicinal plant in Ayurveda.
Multiple shoot cultures of two experimental lines of Withania somnifera plants (RS-Selection-1 and RS-Selection-2) were… 
Highly Cited
2002
Highly Cited
2002
Axon- or dendrite-predominant outgrowth induced by constituents from Ashwagandha
We previously reported that the methanol extract of Ashwagandha (roots of Withania somnifera Dunal) induced dendrite extension in… 
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