Wiskott-Aldrich Syndrome Protein

Known as: WASP Protein, Wiskott Aldrich Syndrome Protein, Wiskott-Aldrich Syndrome Protein [Chemical/Ingredient] 
WASP protein is mutated in WISKOTT-ALDRICH SYNDROME and is expressed primarily in hematopoietic cells. It is the founding member of the WASP protein… (More)
National Institutes of Health

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In BloodProcess of secretionWAS geneWAS wt Allele
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WAS protein, human

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Highly Cited
2007
Highly Cited
2007
WIP is a chaperone for Wiskott-Aldrich syndrome protein (WASP).
Wiskott-Aldrich syndrome protein (WASP) is in a complex with WASP-interacting protein (WIP). WASP levels, but not mRNA levels… (More)
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Highly Cited
2007
Highly Cited
2007
Wiskott-Aldrich syndrome protein is required for regulatory T cell homeostasis.
Wiskott-Aldrich syndrome protein (WASp) is essential for optimal T cell activation. Patients with WAS exhibit both… (More)
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Highly Cited
2003
Highly Cited
2003
SLP-76 coordinates Nck-dependent Wiskott-Aldrich syndrome protein recruitment with Vav-1/Cdc42-dependent Wiskott-Aldrich syndrome protein activation at the T cell-APC contact site.
We have shown previously that Wiskott-Aldrich syndrome protein (WASP) activation at the site of T cell-APC interaction is a two… (More)
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Highly Cited
2000
Highly Cited
2000
Activation by Cdc42 and Pip2 of Wiskott-Aldrich Syndrome Protein (Wasp) Stimulates Actin Nucleation by Arp2/3 Complex
We purified native WASp (Wiskott-Aldrich Syndrome protein) from bovine thymus and studied its ability to stimulate actin… (More)
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Highly Cited
1999
Highly Cited
1999
Wiskott-Aldrich syndrome protein regulates podosomes in primary human macrophages.
Wiskott-Aldrich syndrome protein (WASp) is a hematopoietic-specific, multidomain protein whose mutation is responsible for the… (More)
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Highly Cited
1999
Highly Cited
1999
Antigen Receptor–Induced Activation and Cytoskeletal Rearrangement Are Impaired in Wiskott-Aldrich Syndrome Protein–Deficient Lymphocytes
The Wiskott-Aldrich syndrome protein (WASp) has been implicated in modulation of lymphocyte activation and cytoskeletal… (More)
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Highly Cited
1999
Highly Cited
1999
Syndapin I, a synaptic dynamin-binding protein that associates with the neural Wiskott-Aldrich syndrome protein.
The GTPase dynamin has been clearly implicated in clathrin-mediated endocytosis of synaptic vesicle membranes at the presynaptic… (More)
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Highly Cited
1998
Highly Cited
1998
Scar1 and the related Wiskott–Aldrich syndrome protein, WASP, regulate the actin cytoskeleton through the Arp2/3 complex
BACKGROUND The actin-related proteins Arp2 and Arp3 are part of a seven-protein complex which is localized in the lamellipodia of… (More)
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Highly Cited
1995
Highly Cited
1995
Wiskott-Aldrich syndrome protein physically associates with Nck through Src homology 3 domains.
In the second of a series of experiments designed to identify p47nck-Src homology 3 (SH3)-binding molecules, we report the… (More)
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Highly Cited
1994
Highly Cited
1994
Isolation of a novel gene mutated in Wiskott-Aldrich syndrome
Wiskott-Aldrich syndrome (WAS) is an X-linked recessive immunodeficiency characterized by eczema, thrombocytopenia, and recurrent… (More)
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