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Wiskott-Aldrich Syndrome Protein

Known as: WASP Protein, Wiskott Aldrich Syndrome Protein, Wiskott-Aldrich Syndrome Protein [Chemical/Ingredient] 
WASP protein is mutated in WISKOTT-ALDRICH SYNDROME and is expressed primarily in hematopoietic cells. It is the founding member of the WASP protein… 
National Institutes of Health

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Related topics

12 relations
In BloodProcess of secretionWAS geneWAS wt Allele

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WAS protein, human

Papers overview

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Highly Cited
2008
Highly Cited
2008
Wiskott-Aldrich syndrome protein deficiency in B cells results in impaired peripheral homeostasis
To more precisely identify the B-cell phenotype in Wiskott-Aldrich syndrome (WAS), we used 3 distinct murine in vivo models to… 
Highly Cited
2004
Highly Cited
2004
A dynamic podosome-like structure of epithelial cells.
Highly Cited
2004
Highly Cited
2004
Cutting Edge: Selective Requirement for the Wiskott-Aldrich Syndrome Protein in Cytokine, but Not Chemokine, Secretion by CD4+ T Cells1
The mechanism of cytokine secretion is not well understood, but cytokines appear to be synthesized and released in a polarized… 
Highly Cited
2003
Highly Cited
2003
Vascular Endothelial Growth Factor Causes Translocation of p47phox to Membrane Ruffles through WAVE1*
Growth factors initiate cytoskeletal rearrangements tightly coordinated with nuclear signaling events. We hypothesized that the… 
Highly Cited
2002
Highly Cited
2002
Individual Hymenoptera Venom Compounds Induce Upregulation of the Basophil Activation Marker Ectonucleotide Pyrophosphatase/Phosphodiesterase 3 (CD203c) in Sensitized Patients
Background: Bee and wasp venom extracts contain potent allergens capable of inducing severe clinical reactions. To analyze… 
Highly Cited
2001
Highly Cited
2001
The Verprolin-like Central (VC) Region of Wiskott-Aldrich Syndrome Protein Induces Arp2/3 Complex-dependent Actin Nucleation*
Wiskott-Aldrich Syndrome protein (WASp) and related proteins stimulate actin filament nucleation by Arp2/3 complex. The isolated… 
Highly Cited
2001
Highly Cited
2001
Coiling Phagocytosis of Borrelia burgdorferiby Primary Human Macrophages Is Controlled by CDC42Hs and Rac1 and Involves Recruitment of Wiskott-Aldrich Syndrome Protein and Arp2/3 Complex
ABSTRACT Lyme borreliosis is a multisystemic disorder primarily affecting the skin, nervous system, and joints. It is caused by… 
Highly Cited
2001
Highly Cited
2001
A Role for Wiskott-Aldrich Syndrome Protein in T-cell Receptor-mediated Transcriptional Activation Independent of Actin Polymerization*
Wiskott-Aldrich syndrome protein (WASP) plays a key role in cytoskeletal rearrangement and transcriptional activation in T-cells… 
Review
2000
Review
2000
The Wiskott–Aldrich syndrome: disordered actin dynamics in haematopoietic cells
The Wiskott-Aldrich syndrome protein (WASp) is a member of a unique family whose members share similar domain structures and are… 
1998
1998
Absence of expression of the Wiskott-Aldrich syndrome protein in peripheral blood cells of Wiskott-Aldrich syndrome patients.
Wiskott-Aldrich syndrome (WAS) is an X-linked primary immunodeficiency that is usually associated with thrombocytopenia and… 
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