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Wiskott-Aldrich Syndrome Protein
Known as:
WASP Protein
, Wiskott Aldrich Syndrome Protein
, Wiskott-Aldrich Syndrome Protein [Chemical/Ingredient]
WASP protein is mutated in WISKOTT-ALDRICH SYNDROME and is expressed primarily in hematopoietic cells. It is the founding member of the WASP protein…
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National Institutes of Health
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Related topics
Related topics
12 relations
In Blood
Process of secretion
WAS gene
WAS wt Allele
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Narrower (1)
WAS protein, human
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2008
Highly Cited
2008
Wiskott-Aldrich syndrome protein deficiency in B cells results in impaired peripheral homeostasis
A. Meyer-Bahlburg
,
S. Becker-Herman
,
+6 authors
D. Rawlings
Blood
2008
Corpus ID: 5734133
To more precisely identify the B-cell phenotype in Wiskott-Aldrich syndrome (WAS), we used 3 distinct murine in vivo models to…
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Highly Cited
2004
Highly Cited
2004
A dynamic podosome-like structure of epithelial cells.
L. Spinardi
,
J. Rietdorf
,
+4 authors
P. Marchisio
Experimental Cell Research
2004
Corpus ID: 24916235
Highly Cited
2004
Highly Cited
2004
Cutting Edge: Selective Requirement for the Wiskott-Aldrich Syndrome Protein in Cytokine, but Not Chemokine, Secretion by CD4+ T Cells1
V. Morales-Tirado
,
Sara Johannson
,
+4 authors
D. Fowell
Journal of Immunology
2004
Corpus ID: 8621945
The mechanism of cytokine secretion is not well understood, but cytokines appear to be synthesized and released in a polarized…
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Highly Cited
2003
Highly Cited
2003
Vascular Endothelial Growth Factor Causes Translocation of p47phox to Membrane Ruffles through WAVE1*
R. Wu
,
Ying Gu
,
Y. Xu
,
F. Nwariaku
,
L. Terada
Journal of Biological Chemistry
2003
Corpus ID: 22831877
Growth factors initiate cytoskeletal rearrangements tightly coordinated with nuclear signaling events. We hypothesized that the…
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Highly Cited
2002
Highly Cited
2002
Individual Hymenoptera Venom Compounds Induce Upregulation of the Basophil Activation Marker Ectonucleotide Pyrophosphatase/Phosphodiesterase 3 (CD203c) in Sensitized Patients
M. Binder
,
G. Fierlbeck
,
T. P. King
,
P. Valent
,
H. Bühring
International Archives of Allergy and Immunology
2002
Corpus ID: 42472271
Background: Bee and wasp venom extracts contain potent allergens capable of inducing severe clinical reactions. To analyze…
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Highly Cited
2001
Highly Cited
2001
The Verprolin-like Central (VC) Region of Wiskott-Aldrich Syndrome Protein Induces Arp2/3 Complex-dependent Actin Nucleation*
K. Hüfner
,
H. Higgs
,
T. Pollard
,
C. Jacobi
,
M. Aepfelbacher
,
S. Linder
Journal of Biological Chemistry
2001
Corpus ID: 13111775
Wiskott-Aldrich Syndrome protein (WASp) and related proteins stimulate actin filament nucleation by Arp2/3 complex. The isolated…
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Highly Cited
2001
Highly Cited
2001
Coiling Phagocytosis of Borrelia burgdorferiby Primary Human Macrophages Is Controlled by CDC42Hs and Rac1 and Involves Recruitment of Wiskott-Aldrich Syndrome Protein and Arp2/3 Complex
S. Linder
,
C. Heimerl
,
V. Fingerle
,
M. Aepfelbacher
,
B. Wilske
Infection and Immunity
2001
Corpus ID: 36320641
ABSTRACT Lyme borreliosis is a multisystemic disorder primarily affecting the skin, nervous system, and joints. It is caused by…
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Highly Cited
2001
Highly Cited
2001
A Role for Wiskott-Aldrich Syndrome Protein in T-cell Receptor-mediated Transcriptional Activation Independent of Actin Polymerization*
Christopher Silvin
,
B. Belisle
,
A. Abo
Journal of Biological Chemistry
2001
Corpus ID: 37212216
Wiskott-Aldrich syndrome protein (WASP) plays a key role in cytoskeletal rearrangement and transcriptional activation in T-cells…
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Review
2000
Review
2000
The Wiskott–Aldrich syndrome: disordered actin dynamics in haematopoietic cells
A. Thrasher
,
S. Burns
,
R. Lorenzi
,
G. Jones
Immunological Reviews
2000
Corpus ID: 8772337
The Wiskott-Aldrich syndrome protein (WASp) is a member of a unique family whose members share similar domain structures and are…
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1998
1998
Absence of expression of the Wiskott-Aldrich syndrome protein in peripheral blood cells of Wiskott-Aldrich syndrome patients.
L. MacCarthy-Morrogh
,
H. Gaspar
,
+5 authors
C. Kinnon
Clinical Immunology and Immunopathology
1998
Corpus ID: 20884867
Wiskott-Aldrich syndrome (WAS) is an X-linked primary immunodeficiency that is usually associated with thrombocytopenia and…
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