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Wf-536

National Institutes of Health

Papers overview

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Highly Cited
2003
Highly Cited
2003
Effect of Wf-536, a novel ROCK inhibitor, against metastasis of B16 melanoma
PurposeRho-associated coiled-coil-forming protein kinase (ROCK) is pivotally involved in invasion by tumor cells and their… 
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2003
2003
WF‐536 INHIBITS METASTATIC INVASION BY ENHANCING THE HOST CELL BARRIER and INHIBITING TUMOUR CELL MOTILITY
1. Rho‐associated coiled‐coil forming protein serine/threonine kinase (ROCK) is involved in the development of tumour metastasis… 
Highly Cited
2003
Highly Cited
2003
Rho kinase and matrix metalloproteinase inhibitors cooperate to inhibit angiogenesis and growth of human prostate cancer xenotransplants
The purpose of this study was to determine the effects of inhibitors of Rho kinase (ROK) and matrix metalloproteinases (MMPs) on… 
Highly Cited
2003
Highly Cited
2003
Wf-536 prevents tumor metastasis by inhibiting both tumor motility and angiogenic actions.
The signaling pathway of Rho and Rho-associated coiled-coil forming protein kinase (ROCK) is involved in tumor metastasis. In the… 
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