Wegener Autoantigen

Known as: Myeloblastin, C-ANCA Antigen, Proteinase 3 
Myeloblastin (256 aa, ~28 kDa) is encoded by the human PRTN3 gene. This protein is involved in the proteolysis of extracellular matrix proteins.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1967-2018
05019672018

Papers overview

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Review
2015
Review
2015
Treatment of patients with rheumatoid arthritis (RA) is rarely personalized, since predictors of disease course are lacking. The… (More)
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Highly Cited
2011
Highly Cited
2011
OBJECTIVE Rheumatoid arthritis (RA) is associated with the presence of anti-citrullinated protein antibodies (ACPAs). Nearly two… (More)
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Highly Cited
2008
Highly Cited
2008
OBJECTIVE Macrophage-derived tumor necrosis factor alpha (TNFalpha) is a dominant mediator of synovitis in rheumatoid arthritis… (More)
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Highly Cited
2008
Highly Cited
2008
OBJECTIVE Anti-citrullinated protein antibodies (ACPAs) display high association with rheumatoid arthritis (RA) and are… (More)
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Highly Cited
2006
Highly Cited
2006
The post-translational modification of histones regulates many cellular processes, including transcription, replication and DNA… (More)
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Highly Cited
2006
Highly Cited
2006
Polycomb response elements (PREs) are specific cis-regulatory sequences needed for transcriptional repression of HOX and other… (More)
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Highly Cited
2003
Highly Cited
2003
We have identified a family of 'Agenet' domains that are plant-specific homologs of Tudor domains. This finding has been extended… (More)
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Highly Cited
1989
Highly Cited
1989
Circulating IgG autoantibodies that produce cytoplasmic immunofluorescence staining of ethanol-fixed normal neutrophils have… (More)
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Highly Cited
1989
Highly Cited
1989
In frogs, mesoderm presumably derives from presumptive ectoderm by induction under the control of diffusible substances produced… (More)
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Highly Cited
1989
Highly Cited
1989
Autoantibodies reacting with the cytoplasm of granulocytes and monocytes (anticytoplasmic antibodies [ACPAs]) were found in 42 of… (More)
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