Myeloblastin

Known as: PRTN3 Gene Protein, C-ANCA Antigen, Proteinase 3 
A polymorphonuclear leukocyte-derived serine protease that degrades proteins such as ELASTIN; FIBRONECTIN; LAMININ; VITRONECTIN; and COLLAGEN. It is… (More)
National Institutes of Health

Papers overview

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Highly Cited
2012
Highly Cited
2012
BACKGROUND Antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis is a severe condition encompassing two major… (More)
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Highly Cited
2003
Highly Cited
2003
We describe a method that allows for the concurrent proteomic analysis of both membrane and soluble proteins from complex… (More)
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Highly Cited
2001
Highly Cited
2001
von Willebrand factor (vWF) is synthesized in megakaryocytes and endothelial cells as a very large multimer, but circulates in… (More)
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Highly Cited
2000
Highly Cited
2000
OBJECTIVE Prediction of relapses in Wegener's granulomatosis (WG) by measuring levels of antineutrophil cytoplasmic antibodies… (More)
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Highly Cited
1999
Highly Cited
1999
Two important cytokines mediating inflammation are tumor necrosis factor alpha (TNFalpha) and IL-1beta, both of which require… (More)
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Highly Cited
1995
Highly Cited
1995
Although specific proteinases play a critical role in the active phase of apoptosis, their substrates are largely unknown. We… (More)
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Highly Cited
1990
Highly Cited
1990
Both the cellular and scrapie isoforms of the prion protein (PrP) designated PrPc and PrPSc are encoded by a single-copy… (More)
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Highly Cited
1989
Highly Cited
1989
Cells from the human leukemia cell line HL-60 undergo terminal differentiation when exposed to inducing agents. Differentiation… (More)
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Highly Cited
1988
Highly Cited
1988
Using a selection for spontaneous mutants that mislocalize a vacuolar carboxypeptidase Y (CPY)-invertase fusion protein to the… (More)
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Highly Cited
1985
Highly Cited
1985
We have found a novel activity in Tetrahymena cell free extracts that adds tandem TTGGGG repeats onto synthetic telomere primers… (More)
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