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Myeloblastin

Known as: PRTN3 Gene Protein, C-ANCA Antigen, Proteinase 3 
A polymorphonuclear leukocyte-derived serine protease that degrades proteins such as ELASTIN; FIBRONECTIN; LAMININ; VITRONECTIN; and COLLAGEN. It is… 
National Institutes of Health

Related topics

Related topics

15 relations
Granulomatosis with polyangiitisIn BloodPRTN3 genePRTN3 wt Allele

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Wegener Autoantigen

Papers overview

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2005
2005
The lysosomal proteinase of Artemia. Purification and characterization.
One single lysosomal proteinase has been found in the dormant gastrulae of Artemia. The enzyme has been purified to homogeneity… 
Review
2003
Review
2003
Membrane proteinase 3 expression on resting neutrophils as a pathogenic factor in PR3-ANCA-associated vasculitis.
Antineutrophil cytoplasm autoantibody (ANCA)-associated small vessel vasculitides are systemic diseases characterized by chronic… 
Review
1996
Review
1996
Anti-neutrophil cytoplasmic antibodies in generalized autoimmune diseases.
Anti-neutrophil cytoplasmic antibodies (ANCA) are a system of autoantibodies which are strongly associated with the primary… 
1991
1991
Autoantibodies against the multicatalytic proteinase in patients with systemic lupus erythematosus
Sera from patients with systemic lupus erythematosus contain specific autoantibodies directed against different polypeptide… 
1991
1991
The nucleotide sequence of 3C proteinase region of the coxsackievirus A24 variant: Comparison of the isolates in Taiwan in 1985–1988
Acute hemorrhagic conjunctivitis caused by coxsackievirus A24 variant (CA24v) first appeared in Taiwan in October 1985, followed… 
1990
1990
The preparation of fully active chymopapain free of contaminating proteinases.
Chymopapain (EC 3.4.22.6) was purified from commercially available dried latex of papaya (Carica papaya) by extraction at acidic… 
1987
1987
Complete amino acid sequence of the A chain of human complement-classical-pathway enzyme C1r.
The amino acid sequence of human C1r A chain was determined, from sequence analysis performed on fragments obtained from C1r… 
1982
1982
Stimulation of Na+-Ca2+ exchange in cardiac sarcolemmal vesicles by proteinase pretreatment.
The Na+-Ca2+ exchange activity of purified canine cardiac sarcolemmal vesicles can be strikingly stimulated if the vesicles are… 
1978
1978
The isolation and properties of a non-pepsin proteinase from human gastric mucosa.
1. A non-pepsin proteinase, proteinase 2, was successfully isolated free from pepsinogen (by repetitive chromatography on DEAE… 
1972
1972
Purification and properties of a human seminal proteinase.
1. A method is described for the purification of a proteinase, present in human seminal plasma and previously shown to accelerate… 
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