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WYE 125132
Known as:
WYE-125132
, WYE125132
National Institutes of Health
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Related topics
Related topics
3 relations
Broader (2)
Phenylurea Compounds
Pyrazoles
Narrower (1)
WYE-132
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2012
2012
Biochemical and pharmacological inhibition of mTOR by rapamycin and an ATP-competitive mTOR inhibitor.
Ker Yu
,
L. Toral-Barza
Methods in molecular biology
2012
Corpus ID: 24373786
The mammalian target of rapamycin (mTOR) is the catalytic subunit of two multiprotein complexes, mTOR complex-1 (mTORC1) and mTOR…
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Highly Cited
2010
Highly Cited
2010
Beyond rapalog therapy: preclinical pharmacology and antitumor activity of WYE-125132, an ATP-competitive and specific inhibitor of mTORC1 and mTORC2.
Ker Yu
,
C. Shi
,
+17 authors
J. Gibbons
Cancer Research
2010
Corpus ID: 7794347
The mammalian target of rapamycin (mTOR) is a major component of the phosphoinositide 3-kinase (PI3K)/AKT signaling pathway that…
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Highly Cited
2010
Highly Cited
2010
Requirement of the mTOR Kinase for the Regulation of Maf1 Phosphorylation and Control of RNA Polymerase III-dependent Transcription in Cancer Cells
Boris Shor
,
Jiang Wu
,
+4 authors
Ker Yu
Journal of Biological Chemistry
2010
Corpus ID: 205296889
The mammalian target of rapamycin (mTOR) regulates growth via promoting translation and transcription. Here, employing an mTOR…
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