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WWC1 wt Allele

Known as: PPP1R168, KIAA0869, MEMRYQTL 
Human WWC1 wild-type allele is located in the vicinity of 5q34 and is approximately 181 kb in length. This allele, which encodes protein KIBRA, is… Expand
National Institutes of Health

Related topics

Related topics

6 relations
5q34Homo sapiensMigration, CellSignal Transduction Inhibition
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Papers overview

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2011
2011
KIBRA polymorphism is related to enhanced memory and elevated hippocampal processing.
Several studies have linked the KIBRA rs17070145 T polymorphism to superior episodic memory in healthy humans. One study… Expand
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2011
2011
Binary regulation of Hippo pathway by Merlin/NF2, Kibra, Lgl, and Melted specifies and maintains postmitotic neuronal fate.
Patterning the Drosophila retina for color vision relies on postmitotic specification of photoreceptor subtypes. R8… Expand
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2011
2011
Frequent epigenetic inactivation of KIBRA, an upstream member of the Salvador/Warts/Hippo (SWH) tumor suppressor network, is associated with specific genetic event in B-cell acute lymphocytic…
The WW-domain containing protein KIBRA has recently been identified as a new member of the Salvador/Warts/Hippo (SWH) pathway in… Expand
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Highly Cited
2010
Highly Cited
2010
Kibra Is a Regulator of the Salvador/Warts/Hippo Signaling Network
The Salvador (Sav)/Warts (Wts)/Hippo (Hpo) (SWH) network controls tissue growth by inhibiting cell proliferation and promoting… Expand
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Highly Cited
2010
Highly Cited
2010
Evidence for an association between KIBRA and late-onset Alzheimer's disease
We recently reported evidence for an association between the individual variation in normal human episodic memory and a common… Expand
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2010
2010
Association study of KIBRA gene with memory performance in a Japanese population.
OBJECTIVES Papassotiropoulos et al. (Science 314: p 475) discovered that a single nucleotide polymorphism (SNP) of the KIBRA gene… Expand
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2010
2010
KIBRA genetic polymorphism influences episodic memory in Alzheimer's disease, but does not show association with disease in a Japanese cohort.
BACKGROUND/AIMS A single-nucleotide polymorphism (SNP) in the KIBRA gene, rs17070145, was reported to be significantly associated… Expand
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2009
2009
Age-dependent association of KIBRA genetic variation and Alzheimer's disease risk
An association between memory performance in healthy young, middle aged an elderly subjects and variability in the KIBRA gene… Expand
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2008
2008
Failure to replicate effect of Kibra on human memory in two large cohorts of European origin.
It was recently suggested that the Kibra polymorphism rs17070145 has a strong effect on multiple episodic memory tasks in humans… Expand
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Highly Cited
2008
Highly Cited
2008
KIBRA genetic polymorphism influences episodic memory in later life, but does not increase the risk of mild cognitive impairment
A common T-->C polymorphism of the KIBRA gene has been recently associated with worse performance on tests of episodic memory… Expand
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