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WRAP53 wt Allele

Known as: TCAB1, DKCB3, WDR79 
Human WRAP53 wild-type allele is located in the vicinity of 17p13.1 and is approximately 17 kb in length. This allele, which encodes telomerase Cajal… Expand
National Institutes of Health

Papers overview

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2015
2015
Background: Telomerase elongation of chromosome ends is restricted within the cell cycle. Results: A human telomerase holoenzyme… Expand
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2013
2013
The maintenance of human telomeres requires the ribonucleoprotein enzyme telomerase, which is composed of telomerase reverse… Expand
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Highly Cited
2012
Highly Cited
2012
The ability of most cancer cells to grow indefinitely relies on the enzyme telomerase and its recruitment to telomeres. In human… Expand
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2012
2012
The regulation of telomere length (TL) is a complex process, requiring the telomerase enzyme complex and numerous regulatory… Expand
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Review
2011
Review
2011
  • Inderjeet S Dokal
  • Hematology. American Society of Hematology…
  • 2011
  • Corpus ID: 24634244
Dyskeratosis congenita (DC) is a multisystem inherited syndrome exhibiting marked clinical and genetic heterogeneity. In its… Expand
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Highly Cited
2011
Highly Cited
2011
Dyskeratosis congenita (DC) is a genetic disorder of defective tissue maintenance and cancer predisposition caused by short… Expand
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Highly Cited
2011
Highly Cited
2011
The differentiation of patient-derived induced pluripotent stem cells (iPSCs) to committed fates such as neurons, muscle and… Expand
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2011
2011
Analysis of numerous genomes has identified a class of regulatory regions that contain a head-to-head arrangement (5' to 5') on… Expand
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2009
2009
Telomerase supports the proliferation of progenitor cells and tumor cells by adding telomere repeats to chromosome ends. The low… Expand
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2007
2007
Germline mutations in the tumor suppressor gene TP53 are associated with high incidence of early-onset malignancies, and somatic… Expand
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