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WR 33278

Known as: 1,3-Propanediamine, N,N''-(dithiodi-2,1-ethanediyl)bis-, WR-33278 
National Institutes of Health

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1 relation

Broader (1)

Mercaptoethylamines

Papers overview

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2002
2002
Selective exclusion by the polyamine transporter as a mechanism for differential radioprotection of amifostine derivatives.
Amifostine metabolites WR-1065 and the disulfide WR-33278 are thiol-containing polyamine analogues with potent radio- and… 
2001
2001
Activation of NFkappaB and MnSOD gene expression by free radical scavengers in human microvascular endothelial cells.
The effect of nonprotein thiol (NPT) free radical scavengers WR-1065 (SH) and WR-33278 (SS), the active thiol and disulfide… 
1997
1997
Repression of c-myc gene expression by the thiol and disulfide forms of the cytoprotector amifostine.
The clinically approved cytoprotector amifostine, designated WR-2721, [S-2-(3-aminopropylamino)ethylphosphorothioic acid… 
1996
1996
Binding of radioprotective thiols and disulfides in Chinese hamster V79 cell nuclei.
Binding of thiols of varying charge (Z) in nuclei prepared in suspension was determined to assess the extent to which histones… 
1995
1995
Involvement of the polyamine transport system in cellular uptake of the radioprotectants WR-1065 and WR-33278.
High levels of the aminothiol WR-1065 protect cells from ionizing radiation, while much lower levels of this compound or its… 
1994
1994
Protection against radiation-induced mutagenesis at the hprt locus by spermine and N,N"-(dithiodi-2,1-ethanediyl)bis-1,3-propanediamine (WR-33278).
The polyamine spermine and the disulfide N,N"-(dithiodi-2,1-ethanediyl)bis-1,3-propanediamine (WR-33278) are structurally similar… 
1982
1982
New methods for analysis of WR-2721, WR-1065, and WR-33278
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