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WR 151327
Known as:
1-Propanethiol, 3-((3-(methylamino)propyl)amino)-, dihydrogen phosphate (ester)
, WR-151327
National Institutes of Health
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Related topics
Related topics
1 relation
Broader (1)
Organothiophosphorus Compounds
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2010
Highly Cited
2010
COMBINED INJURY: FACTORS WITH POTENTIAL TO IMPACT RADIATION DOSE ASSESSMENTS
G. D. Ledney
,
T. Elliott
Health Physics
2010
Corpus ID: 36497835
Combined injuries, which are expected after a radiation dispersal device release or nuclear weapon detonation, are the…
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2001
2001
Radioprotective and locomotor responses of mice treated with nimodipine alone and in combination with WR‐151327
M. Landauer
,
C. A. Castro
,
K. A. Benson
,
J. Hogan
,
J. Weiss
Journal of Applied Toxicology
2001
Corpus ID: 23835173
The effect of combining a radiation‐protective phosphorothioate with another agent was investigated in an attempt to increase…
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2000
2000
WR-151327 increases resistance to Klebsiella pneumoniae infection in mixed-field- and gamma-photon-irradiated mice.
G. D. Ledney
,
T. Elliott
,
R. A. Harding
,
W. Jackson
,
C. E. Inal
,
M. Landauer
International Journal of Radiation Biology
2000
Corpus ID: 31627402
PURPOSE To determine the efficacy of WR-151327 (WR) [S-3-(3-methylaminopropylamino) propylphosphorothioic acid; (CH3-HN-(CH2)3-NH…
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1994
1994
Preclinical evaluation of WR-151327: an orally active chemotherapy protector.
D. Green
,
D. Bensely
,
P. Schein
Cancer Research
1994
Corpus ID: 21282828
Clinical trials are in progress to evaluate radio- and chemoprotection by the aminothiol 2-[(3-aminopropyl)amino]ethanethiol…
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1994
1994
Organic thiophosphate WR-151327 suppresses expression of HIV in chronically infected cells.
T. Kalebic
,
P. Schein
AIDS Research and Human Retroviruses
1994
Corpus ID: 28101969
Reducing agents such as glutathione (GSH), glutathione ester (GSE), and N-acetylcysteine (NAC) have been shown to suppress the…
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1994
1994
Survival of irradiated mice treated with WR-151327, synthetic trehalose dicorynomycolate, or ofloxacin.
G. D. Ledney
,
T. Elliott
,
+4 authors
S. Tom
Advances in Space Research
1994
Corpus ID: 24261390
1992
1992
Pathological evaluation of WR-151327 administered orally in irradiated and non-irradiated male mice.
L. Steel-Goodwin
,
J. Kendrick
,
J. Egan
,
J. Eckstein
Annals of Clinical and Laboratory Science
1992
Corpus ID: 34358795
Studies were made on the radioprotective and toxic effects of orally administered WR-151327 in male CD2F1 mice. The lowest dose…
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1991
1991
Protection by WR-151327 against late-effect damage from fission-spectrum neutrons.
D. Grdina
,
B. J. Wright
,
B. Carnes
Radiation Research
1991
Corpus ID: 23939009
The mutagenic and carcinogenic properties of fission-spectrum neutrons (KERMA-weighted mean energy of 0.85 MeV) from Argonne…
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1990
1990
Pathological effects of the radiation protector WR-151327 in mice.
M. V. van Beek
,
R. Doak
,
C. Sigdestad
,
D. Grdina
Radiation Research
1990
Corpus ID: 20976033
The systemic effects of the radiation protective agent, S-3-(3-methylaminopropylamino) propylphosphorothioic acid (WR-151327…
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1987
1987
Protection of mice against fission neutron irradiation by WR-2721 or WR-151327.
L. Steel
,
A. J. Jacobs
,
L. Giambarresi
,
W. Jackson
Radiation Research
1987
Corpus ID: 25434461
Two phosphorothioate compounds, WR-2721 and WR-151327, were examined for their radioprotective efficacies against the effects of…
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