Skip to search formSkip to main contentSkip to account menu

WISP3 gene

Known as: WISP3, WNT1-INDUCIBLE SIGNALING PATHWAY PROTEIN 3, WNT1 inducible signaling pathway protein 3 
This gene plays a role in signal transduction and intercellular signaling. It is involved in postnatal skeletal growth and cartilage homeostasis
National Institutes of Health

Related topics

Related topics

3 relations
Signal TransductionWISP3 protein, humanskeletal development

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
CCN3, a key matricellular protein, distinctly inhibits TGFβ1-mediated Smad1/5/8 signalling in human podocyte culture.
Growth factors like TGFβ and CTGF (CCN2) plays a vital role in various cellular functions. TGFβ and CTGF are overexpressed in… 
2016
2016
The matricellular protein CCN6 (WISP3) decreases Notch1 and suppresses breast cancer initiating cells
Increasing evidence supports that the epithelial to mesenchymal transition (EMT) in breast cancer cells generates tumor… 
2015
2015
Identification of a mutation in the WISP3 gene in three unrelated families with progressive pseudorheumatoid dysplasia.
Progressive pseudorheumatoid dysplasia (PPD) is a rare autosomal recessive genetic disease, which is caused by the functional… 
2015
2015
WISP 3 ( CCN 6 ) Regulates Milk Protein Synthesis and Cell Growth Through mTOR Signaling in Dairy Cow Mammary Epithelial Cells
The mTOR/S6K1 signaling pathway is the primary regulator of milk protein synthesis. While mTOR is known to be regulated at the… 
2013
2013
Decoding the knots of initiation of oncogenic epithelial-mesenchymal transition in tumor progression.
Oncogenic epithelial-mesenchymal transition (oncEMT) plays important roles in the genesis of cancer stem cells (CSCs), malignant… 
2013
2013
CCN6: a novel method of aTAKing cancer
It is well-established that the expression of CCN family of matricellular proteins is altered in essentially all cancers and… 
2011
2011
CCN3/NOV small interfering RNA enhances fibrogenic gene expression in primary hepatic stellate cells and cirrhotic fat storing cell line CFSC
Nephroblastoma overexpressed gene encodes a matricellular protein (CCN3/NOV) of the CCN family, comprising CCN1 (CYR61), CCN2… 
2011
2011
A homozygous recurring mutation in WISP3 causing progressive pseudorheumatoid arthropathy
Abstract WISP3 is a member of the CCN (for CTGF, CYR61, and NOV) gene family, which encodes cysteine-rich secreted proteins with… 
2007
2007
Cellular and molecular responses in progressive pseudorheumatoid dysplasia articular cartilage associated with compound heterozygous WISP3 gene mutation
Progressive pseudorheumatoid dysplasia (PPD) is characterized by continuous degeneration and loss of articular cartilage, which… 
Review
2004
Review
2004
[Pathology and molecular pathogenesis of spondyloepiphyseal dysplasia tarda with progressive arthropathy caused by compound CCN6 heterogeneous gene mutations].
OBJECTIVE To characterize the clinical manifestations, features of roentgenography and MR imaging, and the pathology of articular… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)