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WISP2 gene

Known as: WISP2, CCN5, CCN FAMILY, MEMBER 5 
This gene plays a role in signal transduction and intercellular signaling. It is involved in the modulation of bone turnover.
National Institutes of Health

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Related topics

2 relations
Signal TransductionWISP2 protein, human

Papers overview

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2015
2015
CCN5 attenuates profibrotic phenotypes of fibroblasts through the Smad6-CCN2 pathway: Potential role in epidural fibrosis
Epidural fibrosis is characterized by the development of dense and thick scar tissue adjacent to the dural mater and ranked as… 
2014
2014
CCN5 overexpression inhibits profibrotic phenotypes via the PI3K/Akt signaling pathway in lung fibroblasts isolated from patients with idiopathic pulmonary fibrosis and in an in vivo model of lung…
Idiopathic pulmonary fibrosis (IPF) is a chronic and progressive interstitial lung disease with unknown etiology and undefined… 
2014
2014
Investigating Microenvironmental Regulation of Human Chordoma Cell Behaviour
The tumour microenvironment is complex and composed of many different constituents, including matricellular proteins such as… 
2013
2013
[Effects of CCN5 overexpression on the expression of alpha-SMA and collagen I in hepatic stellate cells and its mechanism].
OBJECTIVE To investigate the relationship between connective tissue growth factor (CCN5) and hepatic stellate cell (HSC… 
2013
2013
Abstract 4385: The green tea polyphenol EGCG induces mesenchymal to epithelial transition (MET) and tumor regression in triple negative breast cancer (TNBC) cells and mouse xenograft model…
Background: Epithelial to Mesenchymal transition (EMT) is an important and coordinated series of events associated with tumor… 
2012
2012
Glucocorticoids induce CCN 5 / WISP-2 expression and attenuate invasion in oestrogen receptor-negative human breast cancer cells
Glucocorticoids induce CCN5/WISP-2 expression and attenuate invasion in oestrogen receptor-negative human breast cancer cells… 
2012
2012
CCN5 Expression in mammals. III. Early embryonic mouse development
CCN proteins play crucial roles in development, angiogenesis, cell motility, matrix turnover, proliferation, and other… 
2011
2011
First Structural Glimpse of CCN3 and CCN5 Multifunctional Signaling Regulators Elucidated by Small Angle X-ray Scattering*
The CCN (cyr61, ctgf, nov) proteins (CCN1–6) are an important family of matricellular regulatory factors involved in internal and… 
2010
2010
Yin and Yang Part Deux: CCN5 inhibits the pro-fibrotic effects of CCN2
There is no treatment for fibrotic disease is a significant cause of mortality. CCN2 Members of the CCN family of matricellular… 
2010
2010
YANG PART DEUX CCN 5 INHIBITS THE PRO-FIBROTIC EFFECTS OF CCN 2
There is no treatment for fibrotic disease is a significant cause of mortality. CCN2 Members of the CCN family of matricellular… 
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