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WHO Central Nervous System Grade IV

Known as: Grade 4, Grade IV, WHO Grade IV 
Describes central nervous system tumors that are generally highly malignant, show rapid and aggressive growth, widely infiltrative, and prone to… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2018
Highly Cited
2018
cIMPACT-NOW update 3: recommended diagnostic criteria for “Diffuse astrocytic glioma, IDH-wildtype, with molecular features of glioblastoma, WHO grade IV”
Working Committee 1 concluded that histologic grade II and III IDH-wildtype diffuse astrocytic gliomas that contain high-level… Expand
  • table 1
2017
2017
Absence of MGMT promoter methylation in diffuse midline glioma, H3 K27M-mutant
Letter According to the revised 4th edition of the WHO classification of tumors of the CNS, diffuse midline gliomas, H3 K27M… Expand
  • figure 1
Review
2017
Review
2017
THE DAY IA IN THE TREATMENT OF GLIOMAS DIED ... 1983 : BTCG trial 8301 begin accrual 1986
The prognosis of patients with glioblastoma, anaplastic astrocytoma, and anaplastic oligodendroglioma remains poor despite… Expand
2017
2017
Diffuse midline gliomas with subclonal H3F3A K27M mutation and mosaic H3.3 K27M mutant protein expression
mutant protein, and discuss the implications with regard to classification and grading. The first patient is a 30-year-old woman… Expand
  • figure 1
2016
2016
Biopsy for diffuse intrinsic pontine glioma: a reappraisal.
Diffuse intrinsic pontine gliomas (DIPGs) are regionally specific gliomas that arise in a relatively narrow age range in children… Expand
2015
2015
Quantitative proteomic analysis of global effect of LLL12 on U87 cell's proteome: An insight into the molecular mechanism of LLL12.
UNLABELLED Glioblastoma multiforme (GBM) is one of the most devastating and dreadful WHO grade IV brain tumors associated with… Expand
2014
2014
Simultaneous discovery of bifrontal meningiomas and a glioblastoma multiforme
A 63-year-old woman presented to her general practitioner with progressive cognitive impairment and chronic headache. MRI of her… Expand
Review
2007
Review
2007
Uncovering Therapeutic Targets FOR Glioblastoma: A Systems Biology Approach
Even though glioblastoma, WHO grade IV (GBM) is one of the most devastating adult cancers, current treatment regimens have not… Expand
Review
2004
Review
2004
Gene therapy of malignant glioma via inhibition of tumor angiogenesis
  • K. Plate
  • Cancer and Metastasis Reviews
  • 2004
    • Corpus ID: 28121068
Malignant gliomas are neuroectodermal tumors which most commonly arise in the white matter of the cerebral hemispheres, and to a… Expand
1976
1976
Prognostic value of serum alpha-fetoprotein in fulminant hepatic failure including patients treated by charcoal haemoperfusion.
Serum alpha-fetoprotein (AFP) levels have been measured sequentially by a radio-immunoassay method in 64 patients with fulminant… Expand
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