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WAY 163909

Known as: WAY-163909, WAY163909 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
Incubation of cocaine cue reactivity associates with neuroadaptations in the cortical serotonin (5-HT) 5-HT2C receptor (5-HT2CR) system
2014
2014
Imaging Evaluation of 5HT2C Agonists, [11C]WAY-163909 and [11C]Vabicaserin, Formed by Pictet–Spengler Cyclization
The serotonin subtype 2C (5HT2C) receptor is an emerging and promising drug target to treat several disorders of the human… 
Highly Cited
2013
Highly Cited
2013
Synergism between a serotonin 5-HT2A receptor (5-HT2AR) antagonist and 5-HT2CR agonist suggests new pharmacotherapeutics for cocaine addiction.
Relapse to cocaine dependence, even after extended abstinence, involves a number of liability factors including impulsivity… 
2011
2011
Serotonergic involvement in methamphetamine-induced locomotor activity: A detailed pharmacological study
Review
2010
Review
2010
Therapeutic Potential of 5-HT2C Receptor Ligands
Serotonin 2C receptors are G protein-coupled receptors expressed by GABAergic, glutamatergic, and dopaminergic neurons… 
2008
2008
WAY-163909, a 5-HT2C agonist, enhances the preclinical potency of current antipsychotics
Introduction5-HT2C agonists, by decreasing mesolimbic dopamine without affecting nigrostriatal dopamine, are predicted to have… 
Highly Cited
2007
Highly Cited
2007
WAY-163909 [(7bR,10aR)-1,2,3,4,8,9,10,10a-Octahydro-7bH-cyclopenta-[b][1,4]diazepino[6,7,1hi]indole]: A Novel 5-Hydroxytryptamine 2C Receptor-Selective Agonist with Preclinical Antipsychotic-Like…
Serotonin-2C (5-HT2C) receptor antagonists and agonists have been shown to affect dopamine (DA) neurotransmission, with agonists… 
Highly Cited
2007
Highly Cited
2007
Antidepressant-like effects of the novel, selective, 5-HT2C receptor agonist WAY-163909 in rodents
RationaleActivation of one or more of the serotonin (5-HT) receptors may play a role in mediating the antidepressant effects of… 
Review
2006
Review
2006
Pharmacological profile of the 5-HT(2C) receptor agonist WAY-163909; therapeutic potential in multiple indications.
The 5-HT(2C) receptor subtype has been implicated in a wide variety of conditions including obesity, anxiety, depression… 
Highly Cited
2005
Highly Cited
2005
WAY-163909 [(7bR, 10aR)-1,2,3,4,8,9,10,10a-Octahydro-7bH-cyclopenta-[b][1,4]diazepino[6,7,1hi]indole], a Novel 5-Hydroxytryptamine 2C Receptor-Selective Agonist with Anorectic Activity
The pharmacological profile of WAY-163909 [(7bR, 10aR)-1,2,3,4,8,9,10,10a-octahydro-7bH-cyclopenta-[b][1,4]diazepino[6,7,1hi… 
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