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WASF2 gene

Known as: SCAR2, WAS protein family member 2, WASP FAMILY, VERPROLIN HOMOLOGY DOMAIN-CONTAINING PROTEIN 2 
This gene is involved in both the mediation of signal transduction and the regulation of cytoskeletal reorganization.
National Institutes of Health

Papers overview

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Highly Cited
2013
Highly Cited
2013
Previous studies have shown that miR-146a acts as either an oncogene or a tumor suppressor in various cancers. In this study, we… Expand
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Highly Cited
2011
Highly Cited
2011
Cell movement begins with a leading edge protrusion, which is stabilized by nascent adhesions and retracted by mature adhesions… Expand
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Highly Cited
2008
Highly Cited
2008
We examined the role of the actin nucleation promoters neural Wiskott-Aldrich syndrome protein (N-WASP) and WAVE2 in cell… Expand
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Highly Cited
2006
Highly Cited
2006
WAVE2 activates the actin-related protein (Arp) 2/3 complex for Rac-induced actin polymerization during lamellipodium formation… Expand
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Highly Cited
2006
Highly Cited
2006
During cadherin-dependent cell-cell adhesion, the actin cytoskeleton undergoes dynamic reorganization in epithelial cells. Rho… Expand
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2005
2005
The bacterial pathogen Salmonella penetrates the intestinal epithelium by inducing its own phagocytosis into epithelial cells… Expand
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Highly Cited
2004
Highly Cited
2004
Polarized cell movement is triggered by the development of a PtdIns(3,4,5)P3 gradient at the membrane, which is followed by… Expand
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Highly Cited
2004
Highly Cited
2004
WAVE2 belongs to a family of proteins that mediates actin reorganization by relaying signals from Rac to the Arp2/3 complex… Expand
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Highly Cited
2003
Highly Cited
2003
Based on grafting experiments, Mangold and Spemann showed the dorsal blastopore lip of an amphibian gastrula to be able to induce… Expand
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2002
2002
We previously reported that IRSp53 binds both Rac and WAVE2, inducing formation of Rac/IRSp53/WAVE2 complex that is important for… Expand
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