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WASF2 gene

Known as: SCAR2, WAS protein family member 2, WASP FAMILY, VERPROLIN HOMOLOGY DOMAIN-CONTAINING PROTEIN 2 
This gene is involved in both the mediation of signal transduction and the regulation of cytoskeletal reorganization.
National Institutes of Health

Papers overview

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Highly Cited
2011
Highly Cited
2011
Cell movement begins with a leading edge protrusion, which is stabilized by nascent adhesions and retracted by mature adhesions… Expand
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Highly Cited
2008
Highly Cited
2008
We examined the role of the actin nucleation promoters neural Wiskott-Aldrich syndrome protein (N-WASP) and WAVE2 in cell… Expand
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Highly Cited
2007
Highly Cited
2007
During cadherin-dependent cell-cell adhesion, the actin cytoskeleton undergoes dynamic reorganization in epithelial cells. Rho… Expand
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Highly Cited
2006
Highly Cited
2006
WAVE2 activates the actin-related protein (Arp) 2/3 complex for Rac-induced actin polymerization during lamellipodium formation… Expand
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Highly Cited
2005
Highly Cited
2005
WAVE2 is a member of the Wiskott-Aldrich syndrome protein family of cytoskeletal regulatory proteins shown to link Rac activation… Expand
Highly Cited
2004
Highly Cited
2004
Polarized cell movement is triggered by the development of a PtdIns(3,4,5)P3 gradient at the membrane, which is followed by… Expand
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Highly Cited
2004
Highly Cited
2004
WAVE2 belongs to a family of proteins that mediates actin reorganization by relaying signals from Rac to the Arp2/3 complex… Expand
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Highly Cited
2003
Highly Cited
2003
WAVE2, a protein related to Wiskott–Aldrich syndrome protein, is crucial for Rac-induced membrane ruffling, which is important in… Expand
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Highly Cited
2003
Highly Cited
2003
The Wiskott–Aldrich syndrome related protein WAVE2 is implicated in the regulation of actin‐cytoskeletal reorganization… Expand
Highly Cited
2003
Highly Cited
2003
Based on grafting experiments, Mangold and Spemann showed the dorsal blastopore lip of an amphibian gastrula to be able to induce… Expand
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