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WASF2 gene

Known as: SCAR2, WAS protein family member 2, WASP FAMILY, VERPROLIN HOMOLOGY DOMAIN-CONTAINING PROTEIN 2 
This gene is involved in both the mediation of signal transduction and the regulation of cytoskeletal reorganization.
National Institutes of Health

Related topics

Related topics

4 relations
Cytoskeletal ModelingSignal TransductionWASF2 protein, humanWASF3 gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2012
Highly Cited
2012
Antioxidant dieckol downregulates the Rac1/ROS signaling pathway and inhibits Wiskott-Aldrich syndrome protein (WASP)-family verprolin-homologous protein 2 (WAVE2)-mediated invasive migration of B16…
Reactive oxygen species (ROS) generation is linked to dynamic actin cytoskeleton reorganization, which is involved in tumor cell… 
2011
2011
Rif-mDia1 Interaction Is Involved in Filopodium Formation Independent of Cdc42 and Rac Effectors
Filopodia are cellular protrusions important for axon guidance, embryonic development, and wound healing. The Rho GTPase Cdc42 is… 
2011
2011
Syk Regulates Multiple Signaling Pathways Leading to CX3CL1 Chemotaxis in Macrophages*
Several studies have clearly established the importance of the interaction between macrophages and CX3CL1 in the progression of… 
2011
2011
Nonmuscle myosin IIA is required for lamellipodia formation through binding to WAVE2 and phosphatidylinositol 3,4,5-triphosphate.
2010
2010
Directional control of WAVE2 membrane targeting by EB1 and phosphatidylinositol 3,4,5-triphosphate.
2009
2009
BetaPIX and GIT1 regulate HGF-induced lamellipodia formation and WAVE2 transport.
2006
2006
Protein kinase A‐dependent increase in WAVE2 expression induced by the focal adhesion protein vinexin
The focal adhesion protein vinexin is a member of a family of adaptor proteins that are thought to participate in the regulation… 
Highly Cited
2005
Highly Cited
2005
WAVE2 Signaling Mediates Invasion of Polarized Epithelial Cells by Salmonella typhimurium*[boxs]
The bacterial pathogen Salmonella penetrates the intestinal epithelium by inducing its own phagocytosis into epithelial cells… 
Highly Cited
2002
Highly Cited
2002
WAVE2 serves a functional partner of IRSp53 by regulating its interaction with Rac.
2001
2001
Requirement of the basic region of N-WASP/WAVE2 for actin-based motility.
WASP family proteins activate nucleation by the Arp2/3 complex, inducing rapid actin polymerization in vitro. Although the C… 
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