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Vitamin K Epoxide Reductase Complex, Subunit 1

Known as: Vitamin K1 2,3-Epoxide Reductase Subunit 1, VKORC1, VKORC1 Protein 
Vitamin K epoxide reductase complex subunit 1 (163 aa, ~18 kDa) is encoded by the human VKORC1 gene. The protein is an integral membrane protein that… 
National Institutes of Health

Related topics

Related topics

5 relations
Enzyme GeneHomo sapiensOxidation-ReductionOxidoreductase Gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2013
Review
2013
Genetic and Clinical Determinants Influencing Warfarin Dosing in Children With Heart Disease
Warfarin is a common anticoagulant with narrow therapeutic window and variable anticoagulation effects. Single gene polymorphisms… 
Review
2013
Review
2013
Expanding Role of Pharmacogenomics in the Management of Cardiovascular Disorders
Cardiovascular disease is a leading cause of death worldwide. Many pharmacologic therapies are available that aim to reduce the… 
2010
2010
Comparison of assay systems for warfarin-related CYP2C9 and VKORC1 genotyping.
2010
2010
Genotype polymorphisms of GGCX, NQO1, and VKORC1 genes associated with risk susceptibility in patients with large-artery atherosclerotic stroke.
2010
2010
A bimodular oxidoreductase mediates the specific reduction of phylloquinone (vitamin K₁) in chloroplasts.
Plants and certain species of cyanobacteria are the only organisms capable of synthesizing phylloquinone (vitamin K₁ for… 
2009
2009
Comparison of performance of three commercial platforms for warfarin sensitivity genotyping.
2008
2008
Enhanced functional recombinant factor VII production by HEK 293 cells stably transfected with VKORC1 where the gamma-carboxylase inhibitor calumenin is stably suppressed by shRNA transfection.
2007
2007
Comparison of the inhibition effect of different anticoagulants on vitamin K epoxide reductase activity from warfarin-susceptible and resistant rat
2006
2006
1173C>T Polymorphism in VKORC1 Modulates the Required Warfarin Dose
The response to warfarin is highly variable among individuals and such variability is likely to have some genetic basis. We… 
2006
2006
Genetic polymorphism of vitamin K epoxide reductase (VKORC1) 1173C>T in a Chinese and a Caucasian population.
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