Vitamin K Epoxide Reductase Complex, Subunit 1

Known as: Vitamin K1 2,3-Epoxide Reductase Subunit 1, VKORC1, VKORC1 Protein 
Vitamin K epoxide reductase complex subunit 1 (163 aa, ~18 kDa) is encoded by the human VKORC1 gene. The protein is an integral membrane protein that… (More)
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
Vitamin K epoxide reductase complex subunit 1 (VKORC1) reduces vitamin K epoxide in the vitamin K cycle for post-translational… (More)
Is this relevant?
2013
2013
BACKGROUND Warfarin directly inhibits vitamin K 2,3-epoxide reductase (VKOR) enzymes. Since the early 1970s, warfarin inhibition… (More)
Is this relevant?
2012
2012
Regulation of key proteins by microRNAs (miRNAs) is an emergent field in biomedicine. Vitamin K 2,3-epoxide reductase complex… (More)
Is this relevant?
2012
2012
Viral interleukin-6 (vIL-6) specified by human herpesvirus 8 is, unlike its cellular counterpart, secreted very inefficiently and… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
2008
2008
OBJECTIVE Besides effects on hemostasis, vitamin K-dependent proteins play a role in bone mineralization and arterial… (More)
  • table 2
  • table 1
  • table 3
Is this relevant?
Review
2006
Review
2006
Vitamin K epoxide, a by-product of the carboxylation of blood coagulation factors, is reduced to vitamin K by an enzymatic system… (More)
Is this relevant?
Highly Cited
2005
Highly Cited
2005
The aim of the study is to explore the contribution of genetic factors related either to drug metabolism (cytochrome P450 2C9) or… (More)
  • table 1
  • figure 1
  • table 2
  • table 3
  • table 4
Is this relevant?
Highly Cited
2005
Highly Cited
2005
OBJECTIVE To evaluate the association of VKORC1 genetic variants with warfarin dose requirements in a Hong Kong Chinese patient… (More)
Is this relevant?
Highly Cited
2005
Highly Cited
2005
Current dosing algorithms do not account for genetic and environmental factors for warfarin dose determinations. This study… (More)
  • table 1
  • figure 1
  • table 2
  • figure 2
  • table 3
Is this relevant?
Highly Cited
2004
Highly Cited
2004
Coumarin derivatives such as warfarin represent the therapy of choice for the long-term treatment and prevention of… (More)
  • figure 1
  • figure 2
  • figure 3
  • table 1
  • figure 1
Is this relevant?