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Viral Oncogene

Cancer-causing genes encoded in viral genomes. Usually denoted v-onc.
National Institutes of Health

Related topics

Related topics

3 relations
ARAF geneNeoplastic Cell TransformationVirus Physiological Phenomena

Papers overview

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Highly Cited
2012
Highly Cited
2012
Distinct clinical features and outcomes in never‐smokers with nonsmall cell lung cancer who harbor EGFR or KRAS mutations or ALK rearrangement
The objectives of this study were to determine the proportions of major oncogenic alterations and to examine survival in genotype… 
Highly Cited
2011
Highly Cited
2011
Coexistence of PIK3CA and Other Oncogene Mutations in Lung Adenocarcinoma–Rationale for Comprehensive Mutation Profiling
Phosphoinositide-3-kinase catalytic alpha polypeptide (PIK3CA) encodes the p110α subunit of the mitogenic signaling protein… 
Highly Cited
2010
Highly Cited
2010
Nuclear factor κB transcription factors are coexpressed and convey a poor outcome in ovarian cancer
Recent work has suggested a role for nuclear factor κB (NF‐κB) in the propagation of ovarian cancer cell lines, but the… 
Highly Cited
2008
Highly Cited
2008
Integration of the HPV16 genome does not invariably result in high levels of viral oncogene transcripts
Virus integration into the host genome is a characteristic step during cervical carcinogenesis. Experimental data provide… 
Review
1993
Review
1993
A comparison of the biological activities of wild‐type and mutant p53
Tumorigenesis is characterized by a series of genetic alterations in both dominant oncogenes and tumor suppressor genes. A… 
Highly Cited
1991
Highly Cited
1991
Preferential expression of c-kit protooncogene transcripts in small cell lung cancer.
Review
1987
Review
1987
Molecular cloning of the akt oncogene and its human homologues AKT1 and AKT2: amplification of AKT1 in a primary human gastric adenocarcinoma.
A previous report described the isolation of a directly transforming retrovirus, AKT8, from a spontaneous thymoma of an AKR mouse… 
Highly Cited
1986
Highly Cited
1986
Requirement for c-ras proteins during viral oncogene transformation
Many retroviral oncogenes have been classified into one of several categories based on structure, enzymology and cellular… 
Highly Cited
1982
Highly Cited
1982
Mouse c-myc oncogene is located on chromosome 15 and translocated to chromosome 12 in plasmacytomas.
Hybridization studies with viral oncogene probes indicate that c-myc, the cellular gene homologous to the transforming gene of… 
Highly Cited
1979
Highly Cited
1979
Three new types of viral oncogene of cellular origin specific for haematopoietic cell transformation
The RNAs of seven replication-defective leukaemia virus (DLV) strains contain three types of unique sequences, which correlate… 
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