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Vancomycin

Known as: Vancomycinum, (2.2Sp,3.5sa,2.6sp)-O(4.2),C(3.4):c(5.4),O(4.6):c(3.5),C(2.7)-tricyclo[N-methyl-D-leucyl-3-chloro-(R)-beta-hydroxy-D-tyrosyl-L-asparaginyl-D-2-(4-{[2-O-(3-amino-2,3,6-trideoxy-3-C-methyl-alpha-L-lyxo-hexopyranosyl)-beta-D-glucopyranosyl]oxy}phenyl)glycyl-D-2-(4-hydroxyphenyl)glycyl-3-chloro-(R)-beta-hydroxy-L-tyrosyl-L-2-(3,5-dihydroxyphenyl)glycine], Vancomycin [Chemical/Ingredient] 
A branched tricyclic glycosylated peptide with bactericidal activity against most organisms and bacteriostatic effect on enterococci. At a site… 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2011
Highly Cited
2011
BACKGROUND Clostridium difficile infection is a serious diarrheal illness associated with substantial morbidity and mortality… 
Review
2010
Review
2010
SUMMARY The emergence of vancomycin-intermediate Staphylococcus aureus (VISA) and heterogeneous vancomycin-intermediate… 
Highly Cited
2008
Highly Cited
2008
ABSTRACT There is growing concern that vancomycin has diminished activity for methicillin-resistant Staphylococcus aureus (MRSA… 
Highly Cited
2006
Highly Cited
2006
  • D. Levine
  • Clinical Infectious Diseases
  • 2006
  • Corpus ID: 34930799
Vancomycin became available for clinical use >50 years ago but was soon discarded in favor of other antibiotics that were deemed… 
Review
2006
Review
2006
  • M. Rybak
  • Clinical Infectious Diseases
  • 2006
  • Corpus ID: 13885863
Vancomycin is one of only a few antibiotics available to treat patients infected with methicillin-resistant Staphylococcus aureus… 
Highly Cited
2003
Highly Cited
2003
Vancomycin-resistant S. aureus was cultured from the exit site of a temporary dialysis catheter of a patient with diabetes… 
Review
2000
Review
2000
  • B. Murray
  • New England Journal of Medicine
  • 2000
  • Corpus ID: 31684251
Enterococci are best known as antibiotic-resistant opportunistic pathogens that are commonly recovered from patients who have… 
Highly Cited
1997
Highly Cited
1997
(MRSA) with reduced suscept-ibility to vancomycin (MIC 8 mg/L). The strain was isolated from a surgical wound infection which was… 
Highly Cited
1988
Highly Cited
1988
THE glycopeptide antibiotic agents vancomycin and teicoplanin are useful in the treatment of severe infections due to gram…