VX 950

Known as: VX-950, VX950 cpd 
 

Topic mentions per year

Topic mentions per year

2004-2014
024620042014

Papers overview

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2008
2008
In patients chronically infected with hepatitis C virus (HCV) strains of genotype 1, rapid and dramatic antiviral activity has… (More)
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2008
2008
An increasing number of new hepatitis C virus NS3-protease inhibitors are being evaluated for the treatment of chronic hepatitis… (More)
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2008
2008
BACKGROUND/AIMS This study assessed the safety and antiviral effects of telaprevir (VX-950) in combination with peginterferon… (More)
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2007
2007
Telaprevir (VX-950) is a highly selective, potent inhibitor of the hepatitis C virus (HCV) NS3.4A serine protease. It has… (More)
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2007
2007
Inhibitors of hepatitis C virus (HCV) protease have shown marked antiviral activity in short-term clinical studies in HCV… (More)
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2007
2007
Previous studies have shown that the total perihepatic lymph node (PLN) volume is (1) associated with the extent of inflammatory… (More)
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Highly Cited
2006
Highly Cited
2006
VX-950 is a potent, selective, peptidomimetic inhibitor of the hepatitis C virus (HCV) NS3-4A serine protease, and it… (More)
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Highly Cited
2006
Highly Cited
2006
BACKGROUND & AIMS VX-950 specifically inhibits the NS3.4A protease of hepatitis C and has antiviral activity in vitro. This phase… (More)
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Highly Cited
2006
Highly Cited
2006
The NS3-4A serine protease of hepatitis C virus (HCV) is essential for viral replication and therefore has been one of the most… (More)
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Highly Cited
2004
Highly Cited
2004
We have used a structure-based drug design approach to identify small molecule inhibitors of the hepatitis C virus (HCV) NS3.4A… (More)
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