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VTRNA2-1 gene

Known as: hvg-5, NC886, CORD BLOOD LYMPHOCYTE-DERIVED NONCODING RNA 3 
National Institutes of Health

Related topics

Related topics

2 relations
MIRN886 microRNA, humanVTRNA1-2 gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2020
Review
2020
Protein kinase R and its cellular regulators in cancer: An active player or a surveillant?
Protein kinase R (PKR), originally known as an antiviral protein, senses various stresses as well as pathogen‐driven double… 
2020
2020
A Regulatory Noncoding RNA, nc886, Suppresses Esophageal Cancer by Inhibiting the AKT Pathway and Cell Cycle Progression
nc886 is a regulatory non-coding RNA (ncRNA) whose expression is frequently silenced in malignancies. In the case of esophageal… 
2020
2020
Uncovering Tumour Heterogeneity through PKR and nc886 Analysis in Metastatic Colon Cancer Patients Treated with 5-FU-Based Chemotherapy
Colorectal cancer treatment has advanced over the past decade. The drug 5-fluorouracil is still used with a wide percentage of… 
Highly Cited
2018
Highly Cited
2018
DNA methylation in blood from neonatal screening cards and the association with BMI and insulin sensitivity in early childhood
Background/Objectives:There is increasing evidence that metabolic diseases originate in early life, and epigenetic changes have… 
2018
2018
The Noncoding RNA nc886 Regulates PKR Signaling and Cytokine Production in Human Cells
Protein kinase RNA-activated (PKR) is a cytoplasmic receptor for dsRNA, and as such is involved in detection of viral infection… 
2018
2018
A human cellular noncoding RNA activates the antiviral protein 2′–5′-oligoadenylate synthetase 1
The 2′–5′-oligoadenylate synthetase (OAS) family of enzymes sense cytosolic dsRNA, a potent signal of viral infection. In… 
2016
2016
nc886, a non-coding RNA and suppressor of PKR, exerts an oncogenic function in thyroid cancer
nc886 is a recently identified cellular non-coding RNA and its depletion leads to acute cell death via PKR (Protein Kinase RNA… 
Highly Cited
2015
Highly Cited
2015
Independent genomewide screens identify the tumor suppressor VTRNA2-1 as a human epiallele responsive to periconceptional environment
BackgroundInterindividual epigenetic variation that occurs systemically must be established prior to gastrulation in the very… 
2014
2014
Variable maternal methylation overlapping the nc886/vtRNA2-1 locus is locked between hypermethylated repeats and is frequently altered in cancer
Cancer is as much an epigenetic disease as a genetic one; however, the interplay between these two processes is unclear. Recently… 
2012
2012
A Tumor Surveillance Model: A Non-Coding RNA Senses Neoplastic Cells and Its Protein Partner Signals Cell Death
nc886 (= pre-miR-886 or vtRNA2-1) is a non-coding RNA that has been recently identified as a natural repressor for the activity… 
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