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VPREB1 gene

Known as: VpreB, CD179A, VPREB1 
National Institutes of Health

Related topics

Related topics

1 relation
VPREB3 gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2015
2015
Surrogate light chain expression beyond the pre-B cell stage promotes tolerance in a dose-dependent fashion.
2013
2013
VPREB 1 deletions occur independent of lambda light chain rearrangement in childhood acute lymphoblastic leukemia
1 Fuxa M, Busslinger M. Reporter gene insertions reveal a strictly B lymphoidspecific expression pattern of Pax5 in support of… 
2004
2004
The human VpreB gene is located on chromosome 22 near a cluster of $${\text{V}}_{\lambda _1 } $$ gene segments
AbstractThe chromosomal location of the human VpreB gene was determined by Southern blotting analysis of restriction enzyme… 
2003
2003
The VpreB1 enhancer drives developmental stage‐specific gene expression in vivo
In adult mice, the VpreB genes are expressed in bone marrow progenitor (pro‐) and precursor (pre‐) B cells. As part of the pre‐B… 
2002
2002
Establishment of novel B-cell precursor leukemia sister cell lines NALM-36 and NALM-37: shift of immunoglobulin phenotype to double light chain positive B-cell.
2001
2001
Analysis of VpreB expression during B lineage differentiation in lambda5-deficient mice.
The VpreB/lambda5 surrogate L chain complex is an essential component of the pre-B cell receptor, the expression of which serves… 
Highly Cited
1999
Highly Cited
1999
Novel mechanisms control the folding and assembly of lambda5/14.1 and VpreB to produce an intact surrogate light chain.
Surrogate light chain, which escorts the mu heavy chain to the cell surface, is a critical component of the pre-B cell receptor… 
1999
1999
Mu-surrogate light chain physicochemical interactions of the human preB cell receptor: implications for VH repertoire selection and cell signaling at the preB cell stage.
The surrogate light chain (SL) composed of the A-like and VpreB polypeptides is organized as two Ig domains and an extra-loop… 
1999
1999
Gene conversion events contribute to the polymorphic variation of the surrogate light chain gene lambda 5/14.1.
Normally occurring and experimentally induced models of immunodeficiency indicate that B cell development and antibody production… 
1995
1995
Kinetic analysis of the interactions of recombinant human VpreB and Ig V domains.
The surrogate light chain, composed of VpreB and lambda 5/14.1 proteins, is selectively expressed on B cell precursors, and is… 
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