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VPREB1 gene

Known as: VpreB, CD179A, VPREB1 
National Institutes of Health

Related topics

Related topics

1 relation
VPREB3 gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
The Expression Pattern of the Pre-B Cell Receptor Components Correlates with Cellular Stage and Clinical Outcome in Acute Lymphoblastic Leukemia
Precursor-B cell receptor (pre-BCR) signaling represents a crucial checkpoint at the pre-B cell stage. Aberrant pre-BCR signaling… 
2016
2016
VpreB serves as an invariant surrogate antigen for selecting immunoglobulin antigen-binding sites
The VpreB component of the surrogate light chain serves as an invariant antigen that may affect the repertoire of antibody… 
Highly Cited
2015
Highly Cited
2015
Genomics and drug profiling of fatal TCF3-HLF-positive acute lymphoblastic leukemia identifies recurrent mutation patterns and therapeutic options
TCF3-HLF−positive acute lymphoblastic leukemia (ALL) is currently incurable. Using an integrated approach, we uncovered distinct… 
2004
2004
Three-dimensional modeling of a pre-B-cell receptor.
Review
2002
Review
2002
The pre-B cell receptor and its role in proliferation and Ig heavy chain allelic exclusion.
2002
2002
The Human V-PreB Promoter Is a Target for Coordinated Activation by Early B Cell Factor and E471
The development of mature B lymphoid cells involves a highly orchestrated regulation of stage- and lineage-specific genes. In… 
Highly Cited
2001
Highly Cited
2001
Loss of Precursor B Cell Expansion but Not Allelic Exclusion in VpreB1/VpreB2 Double-Deficient Mice
The pre-B cell receptor consists of immunoglobulin (Ig) μ heavy chains and surrogate light chain, i.e., the VpreB and λ5 proteins… 
Highly Cited
1999
Highly Cited
1999
Novel mechanisms control the folding and assembly of lambda5/14.1 and VpreB to produce an intact surrogate light chain.
Surrogate light chain, which escorts the mu heavy chain to the cell surface, is a critical component of the pre-B cell receptor… 
1994
1994
Molecular components and assembly of mu.surrogate light chain complexes in pre-B cell lines.
1993
1993
Structure, biosynthesis, and transduction properties of the human mu-psi L complex: similar behavior of preB and intermediate preB-B cells in transducing ability.
In human preB cells, the mu chain is associated with a surrogate light chain composed of the VpreB and lambda-like gene products… 
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