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VPREB1 gene

Known as: VpreB, CD179A, VPREB1 
 
National Institutes of Health

Papers overview

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Highly Cited
2015
Highly Cited
2015
TCF3-HLF−positive acute lymphoblastic leukemia (ALL) is currently incurable. Using an integrated approach, we uncovered distinct… Expand
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2012
2012
Children with Down’s syndrome (DS) have an increased risk of developing acute lymphoblastic leukemia (ALL) and have a low… Expand
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2004
2004
Signals delivered by the immunoglobulin (Ig)-like pre-B-cell receptor (pre-BCR) are critical for efficient maturation of early… Expand
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2004
2004
B lymphocyte development is a complex biological process critically dependent on the transcription factor early B cell factor… Expand
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Highly Cited
2001
Highly Cited
2001
The pre-B cell receptor consists of immunoglobulin (Ig) mu heavy chains and surrogate light chain, i.e., the VpreB and lambda5… Expand
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1999
1999
Surrogate light chain, which escorts the mu heavy chain to the cell surface, is a critical component of the pre-B cell receptor… Expand
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1999
1999
Normally occurring and experimentally induced models of immunodeficiency indicate that B cell development and antibody production… Expand
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1998
1998
The VpreB and lambda 5 genes encode proteins that associate non-covalently to form the so-called surrogate light (SL) chain. The… Expand
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1996
1996
The surrogate light chain is composed of two polypeptides, VpreB and lambda 5. In the mouse there are two VpreB genes which are… Expand
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1993
1993
In human preB cells, the mu chain is associated with a surrogate light chain composed of the VpreB and lambda-like gene products… Expand
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