Skip to search formSkip to main contentSkip to account menu

VPREB1 gene

Known as: VpreB, CD179A, VPREB1 
National Institutes of Health

Related topics

Related topics

1 relation
VPREB3 gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2013
2013
VPREB 1 deletions occur independent of lambda light chain rearrangement in childhood acute lymphoblastic leukemia
1 Fuxa M, Busslinger M. Reporter gene insertions reveal a strictly B lymphoidspecific expression pattern of Pax5 in support of… 
2012
2012
B lymphopoiesis is characterized by pre-B cell marker gene expression in fetal cattle and declines in adults.
2006
2006
Only VpreB1, but not VpreB2, is expressed at levels which allow normal development of B cells.
The surrogate light chain (SLC) consists of the polypeptides lambda5 and, in the mouse, either VpreB1 or VpreB2. SLC associates… 
2004
2004
The human VpreB gene is located on chromosome 22 near a cluster of $${\text{V}}_{\lambda _1 } $$ gene segments
AbstractThe chromosomal location of the human VpreB gene was determined by Southern blotting analysis of restriction enzyme… 
2002
2002
The Human V-PreB Promoter Is a Target for Coordinated Activation by Early B Cell Factor and E471
The development of mature B lymphoid cells involves a highly orchestrated regulation of stage- and lineage-specific genes. In… 
Highly Cited
1999
Highly Cited
1999
Novel mechanisms control the folding and assembly of lambda5/14.1 and VpreB to produce an intact surrogate light chain.
Surrogate light chain, which escorts the mu heavy chain to the cell surface, is a critical component of the pre-B cell receptor… 
1999
1999
Mu-surrogate light chain physicochemical interactions of the human preB cell receptor: implications for VH repertoire selection and cell signaling at the preB cell stage.
The surrogate light chain (SL) composed of the A-like and VpreB polypeptides is organized as two Ig domains and an extra-loop… 
1998
1998
Identification of a tissue‐ and differentiation stage‐specific enhancer of the VpreB1 gene
The VpreB and λ5 genes encode proteins that associate non‐covalently to form the so‐called surrogate light (SL) chain. The SL… 
1995
1995
Kinetic analysis of the interactions of recombinant human VpreB and Ig V domains.
The surrogate light chain, composed of VpreB and lambda 5/14.1 proteins, is selectively expressed on B cell precursors, and is… 
1992
1992
Pre‐B lymphocyte‐specific transcriptional control of the mouse VpreB gene
The VpreB genes, which encode surrogate immunoglobulin light chain molecules, are expressed as RNA almost exclusively in pre‐B… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)