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VPRBP wt Allele

Known as: KIAA0800, MGC102804, DCAF1 
Human VPRBP wild-type allele is located in the vicinity of 3p21.2 and is approximately 101 kb in length. This allele, which encodes protein VPRBP, is… Expand
National Institutes of Health

Papers overview

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Highly Cited
2012
Highly Cited
2012
The sterile alpha motif and HD domain-containing protein-1 (SAMHD1) inhibits infection of myeloid cells by human and related… Expand
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Highly Cited
2012
Highly Cited
2012
Ubiquitination plays a major role in protein degradation. Although phosphorylation-dependent ubiquitination is well known for the… Expand
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Highly Cited
2010
Highly Cited
2010
Current models imply that the FERM domain protein Merlin, encoded by the tumor suppressor NF2, inhibits mitogenic signaling at or… Expand
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2010
2010
Vpx and Vpr are related lentiviral accessory proteins that enhance virus replication in macrophages and dendritic cells. Both… Expand
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Highly Cited
2008
Highly Cited
2008
Vpx is a small virion-associated adaptor protein encoded by viruses of the HIV-2/SIVsm lineage of primate lentiviruses that… Expand
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Highly Cited
2008
Highly Cited
2008
Human immunodeficiency virus type 2 (HIV-2)/simian immunodeficiency virus SIV(SM) Vpx is incorporated into virion particles and… Expand
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Highly Cited
2007
Highly Cited
2007
How the HIV1 Vpr protein initiates the host cell response leading to cell cycle arrest in G(2) has remained unknown. Here, we… Expand
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Highly Cited
2007
Highly Cited
2007
The roles of the HIV1 protein Vpr in virus replication and pathogenesis remain unclear. Expression of Vpr in dividing cells… Expand
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Highly Cited
2007
Highly Cited
2007
HIV-1 Vpr is a viral accessory protein that activates ATR through the induction of DNA replication stress. ATR activation results… Expand
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Highly Cited
2007
Highly Cited
2007
Vpr-mediated induction of G2 cell cycle arrest has been postulated to be important for human immunodeficiency virus type 1 (HIV-1… Expand
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