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VPRBP gene

Known as: KIAA0800, VPRBP, DCAF1 
This gene plays a role in protein ubiquitination.
National Institutes of Health

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1 relation
VprBP protein, human

Papers overview

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2018
2018
Experimental design and data analysis of Ago‐RIP‐Seq experiments for the identification of microRNA targets
&NA; The identification of microRNA (miRNA) target genes is crucial for understanding miRNA function. Many methods for the genome… 
2016
2016
HIV-1 Vpr increases HCV replication through VprBP in cell culture.
Review
2015
Review
2015
RIP-Seq data analysis to determine RNA-protein associations.
Next-generation sequencing (NGS) technologies have opened new avenues of unprecedented power for research in molecular biology… 
2015
2015
Tumor suppressor protein Lgl mediates G1 cell cycle arrest at high cell density by forming an Lgl-VprBP-DDB1 complex
Lgl is a conserved tumor suppressor suggested to be involved in cell polarity regulation and suppression of cell proliferation… 
2015
2015
VprBP Is Required for Efficient Editing and Selection of Igκ+ B Cells, but Is Dispensable for Igλ+ and Marginal Zone B Cell Maturation and Selection
B cell development past the pro-B cell stage in mice requires the Cul4-Roc1-DDB1 E3 ubiquitin ligase substrate recognition… 
2014
2014
Defining the Interactions and Role of DCAF1/VPRBP in the DDB1-Cullin4A E3 Ubiquitin Ligase Complex Engaged by HIV-1 Vpr to Induce a G2 Cell Cycle Arrest
HIV viral protein R (Vpr) induces a cell cycle arrest at the G2/M phase by activating the ATR DNA damage/replication stress… 
2014
2014
Structural basis of DDB1‐and‐Cullin 4‐associated Factor 1 (DCAF1) recognition by merlin/NF2 and its implication in tumorigenesis by CD44‐mediated inhibition of merlin suppression of DCAF1 function
Merlin, a tumor suppressor encoded by the neurofibromatosis type 2 gene, has been shown to suppress tumorigenesis by inhibiting… 
2013
2013
HIV-2 and SIVmac Accessory Virulence Factor Vpx Down-regulates SAMHD1 Enzyme Catalysis Prior to Proteasome-dependent Degradation*
Background: SAMHD1 is counteracted by the HIV-2/SIV virulence factor Vpx, which directs it for degradation. Results: Vpx in… 
2002
2002
Sox9 transactivation and testicular expression of a novel human gene, KIAA0800
The Sry and Sox9 sex‐determination factors initiate and promote testis differentiation by gene transactivation through similar… 
2001
2001
Constitutive beta cell expression of IL-12 does not perturb self-tolerance but intensifies established autoimmune diabetes.
To analyze the function of the Th1-promoting cytokine IL-12 in vivo, we generated transgenic (tg) mice (RIP-IL12 mice) whose… 
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