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VPC23019

 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (1)

Phosphoserine
analogs & derivatives

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2011
2011
HDL and sphingosine‐1‐phosphate activate stat3 in prostate cancer DU145 cells via ERK1/2 and S1P receptors, and promote cell migration and invasion
Androgen deprivation therapy in men with prostate cancer leads to a significant increase of high density lipoprotein (HDL), but… Expand
Highly Cited
2010
Highly Cited
2010
Activation of Sphingosine 1-Phosphate Receptor-1 by FTY720 Is Neuroprotective After Ischemic Stroke in Rats
Background and Purpose— FTY720 is a known sphingosine 1–phosphate receptor agonist. In the present study, we investigated the… Expand
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Highly Cited
2010
Highly Cited
2010
Sphingosine 1-Phosphate (S1P) Regulates Vascular Contraction via S1P3 Receptor: Investigation Based on a New S1P3 Receptor Antagonist
Sphingosine 1-phosphate (S1P) induces diverse biological responses in various tissues by activating specific G protein-coupled… Expand
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2009
2009
Different response patterns of several ligands at the sphingosine‐1‐phosphate receptor subtype 3 (S1P3)
Background and purpose:  Recently, some ligands targeting the sphingosine‐1‐phosphate receptor subtype 3 (S1P3) have become… Expand
Highly Cited
2008
Highly Cited
2008
Analysis of sphingosine 1‐phosphate receptors involved in constriction of isolated cerebral arteries with receptor null mice and pharmacological tools
Sphingosine 1‐phosphate (S1P) selectively and potently constricts isolated cerebral arteries, but this response has not been… Expand
Highly Cited
2008
Highly Cited
2008
HDL-Associated Lysosphingolipids Inhibit NAD(P)H Oxidase–Dependent Monocyte Chemoattractant Protein-1 Production
Objectives—High-density lipoprotein (HDL) levels are inversely proportional to the risk of atherosclerosis, but mechanisms of HDL… Expand
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Highly Cited
2007
Highly Cited
2007
Essential Roles of Sphingosine 1‐Phosphate/S1P1 Receptor Axis in the Migration of Neural Stem Cells Toward a Site of Spinal Cord Injury
Neural stem/progenitor cells (NSPCs) migrate toward a damaged area of the central nervous system (CNS) for the purpose of… Expand
Highly Cited
2007
Highly Cited
2007
Deletion of the sphingosine kinase-1 gene influences cell fate during hypoxia and glucose deprivation in adult mouse cardiomyocytes.
OBJECTIVES Activation of sphingosine kinase (SphK), which has two known isoforms, is responsible for the synthesis of sphingosine… Expand
Highly Cited
2006
Highly Cited
2006
Insulin-like Growth Factors Mediate Heterotrimeric G Protein-dependent ERK1/2 Activation by Transactivating Sphingosine 1-Phosphate Receptors*
Although several studies have shown that a subset of insulin-like growth factor (IGF) signals require the activation of… Expand
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Highly Cited
2005
Highly Cited
2005
Sphingosine 1-Phosphate Analogs as Receptor Antagonists*
Sphingosine 1-phosphate (S1P) is a lysophospholipid mediator that evokes a variety of cell and tissue responses via a set of cell… Expand
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