VPC 12249

Known as: VPC-12249, VPC12249 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

2001-2016
01220012016

Papers overview

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2014
2014
Lysophosphatidic acid (LPA) is a natural bioactive lipid that acts through six different G protein-coupled receptors (LPA1-6… (More)
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2011
2011
Lung fibrosis is a common and serious complication of radiation therapy for lung cancer, for which there are no efficient… (More)
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2010
2010
Radiation pneumonitis (RP) is a serious complication of radiation therapy for thoracic tumors. Lysophosphatidic acid (LPA) and… (More)
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2008
2008
Although lysophosphatidic acid (LPA) is known to increase intracellularfree calcium concentration ([Ca(2+)](i)) in different cell… (More)
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Highly Cited
2004
Highly Cited
2004
Cytokines and growth factors in malignant ascites are thought to modulate a variety of cellular activities of cancer cells and… (More)
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2004
2004
A recently reported dual LPA1/LPA3 receptor antagonist (VPC12249, 1) has been modified herein so as to optimize potency and… (More)
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2003
2003
Lysophosphatidic acid (LPA) is a bioactive lysophospholipid mediator that acts through G protein-coupled receptors. Most cell… (More)
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2003
2003
Lysophosphatidic acid (LPA) released during ischemia has diverse physiological effects via its G protein-coupled receptors, LPA1… (More)
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2001
2001
The physiological implications of lysophosphatidic acid occupancy of individual receptors are largely unknown because selective… (More)
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2001
2001
The physiological implications of lysophosphatidic acid occupancy of individual receptors are largely unknown because selective… (More)
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Is this relevant?