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VPC 12249
Known as:
VPC-12249
, VPC12249
National Institutes of Health
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
Lysophosphatidic Acid Receptor Type 1 (LPA1) Plays a Functional Role in Osteoclast Differentiation and Bone Resorption Activity*
M. David
,
I. Machuca‐Gayet
,
+12 authors
O. Peyruchaud
Journal of Biological Chemistry
2014
Corpus ID: 5322777
Background: Lysophosphatidic acid (LPA) is a bioactive lipid with pleiotropic activities due to activation of six receptors (LPA1…
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2014
2014
Regulation of silicosis formation by lysophosphatidic acid and its receptors
C. Cong
,
L. Mao
,
Yanlin Zhang
,
Zan-mei Zhao
,
Xi-xian Xu
,
Jin-yuan Zhao
Experimental Lung Research
2014
Corpus ID: 28668078
ABSTRACT Silicosis is a serious occupational disease characterized by lung fibrosis that is caused by long-term inhalation of…
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2013
2013
Temporal expression of hippocampal lysophosphatidic acid receptors and their roles in kainic acid-induced neurotoxicity
Jin-Koo Lee
,
Min-Soo Kwon
,
+4 authors
H. Suh
Genes & Genomics
2013
Corpus ID: 256060391
In this investigation, the role of hippocampal lysophosphatidic acid (LPA) receptors in the regulation of kainic acid (KA…
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Highly Cited
2011
Highly Cited
2011
Blockade of lysophosphatidic acid receptors LPAR1/3 ameliorates lung fibrosis induced by irradiation.
L. Gan
,
J. Xue
,
+6 authors
Wei Jiang
Biochemical and Biophysical Research…
2011
Corpus ID: 205915932
2010
2010
Effects of lysophosphatidic acid and its receptors LPA⅓ on radiation pneumonitis.
J. Xue
,
L. Gan
,
+8 authors
You Lu
Oncology Report
2010
Corpus ID: 20960931
Radiation pneumonitis (RP) is a serious complication of radiation therapy for thoracic tumors. Lysophosphatidic acid (LPA) and…
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2008
2008
Mechanisms of the lysophosphatidic acid-induced increase in [Ca2+]i in skeletal muscle cells
Yan‐Jun Xu
,
P. Tappia
,
R. Goyal
,
N. Dhalla
Journal of Cellular and Molecular Medicine
2008
Corpus ID: 15366717
Although lysophosphatidic acid (LPA) is known to increase intracellularfree calcium concentration ([Ca2+]i) in different cell…
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Highly Cited
2004
Highly Cited
2004
Initial structure-activity relationships of lysophosphatidic acid receptor antagonists: discovery of a high-affinity LPA1/LPA3 receptor antagonist.
B. Heasley
,
Renata Jarosz
,
K. Lynch
,
T. Macdonald
Bioorganic & Medicinal Chemistry Letters
2004
Corpus ID: 29394830
Highly Cited
2003
Highly Cited
2003
Identification of a Phosphothionate Analogue of Lysophosphatidic Acid (LPA) as a Selective Agonist of the LPA3 Receptor*
Yutaka Hasegawa
,
J. R. Erickson
,
+11 authors
X. Fang
Journal of Biological Chemistry
2003
Corpus ID: 25769228
Lysophosphatidic acid (LPA) is a bioactive lysophospholipid mediator that acts through G protein-coupled receptors. Most cell…
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Highly Cited
2003
Highly Cited
2003
Selective blockade of lysophosphatidic acid LPA3 receptors reduces murine renal ischemia-reperfusion injury.
M. Okusa
,
H. Ye
,
Liping Huang
,
Laura Sigismund
,
T. Macdonald
,
K. Lynch
AJP - Renal Physiology
2003
Corpus ID: 45790134
Lysophosphatidic acid (LPA) released during ischemia has diverse physiological effects via its G protein-coupled receptors, LPA1…
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Highly Cited
2001
Highly Cited
2001
Activity of 2-substituted lysophosphatidic acid (LPA) analogs at LPA receptors: discovery of a LPA1/LPA3 receptor antagonist.
C. Heise
,
W. Santos
,
+4 authors
K. Lynch
Molecular Pharmacology
2001
Corpus ID: 15819319
The physiological implications of lysophosphatidic acid occupancy of individual receptors are largely unknown because selective…
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