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VNP 20009

Known as: Salmonella VNP20009, VNP-20009, VNP20009 
A genetically stable Salmonella typhimurium strain, attenuated by chromosomal deletion of the purI and msbB genes, with tumor-targeting activity. In… 
National Institutes of Health

Related topics

Related topics

5 relations

Broader (2)

Bacterial VaccinesLive, Attenuated Salmonella Typhimurium
NCIt Antineoplastic Agent TerminologySalmonellaTapet

Papers overview

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2018
2018
Evaluation of truncated G protein delivered by live attenuated Salmonella as a vaccine against respiratory syncytial virus.
2018
2018
Co-expression of a Chimeric Protease Inhibitor Secreted by a Tumor-targeted Salmonella Protects Therapeutic Proteins from Proteolytic Degradation.
Sunflower trypsin inhibitor (SFTI) is a 14 amino acid bicyclic peptide that contains a single internal disulfide bond. We… 
Review
2017
Review
2017
Is LukS-PV a novel experimental therapy for leukemia?
2016
2016
Salmonella VNP20009-mediated RNA interference of ABCB5 moderated chemoresistance of melanoma stem cell and suppressed tumor growth more potently
Drug resistance remains an obstacle hindering the success of chemotherapy. Cancer stem cells (CSCs) have been recently found to… 
2015
2015
Obligate anaerobic Salmonella typhimurium strain YB1 treatment on xenograft tumor in immunocompetent mouse model.
The present authors have previously reported a novel approach to genetically engineer Salmonella typhimurium for the medically… 
2013
2013
Tumor growth control with IDO-silencing Salmonella--reply.
The letter by Hoffman states that Salmonella typhimurium ( S. typhimurium ) A1-R alone could be equally, or more, efficient in… 
2007
2007
Salmonella–Host Cell Interactions, Changes in Host Cell Architecture, and Destruction of Prostate Tumor Cells with Genetically Altered Salmonella
Increasingly, genetically modified Salmonella are being explored as a novel treatment for cancer because Salmonella… 
Review
2004
Review
2004
Suicide gene therapy : methods and reviews
Introduction to the Background, Principles, and State of the Art in Suicide Gene Therapy Ion Niculescu-Duvaz and Caroline J… 
Review
2002
Review
2002
Live bacteria as anticancer agents and tumor-selective protein delivery vectors.
The development of novel cancer therapies that are selective for cancer cells with limited toxicity to normal tissues is a… 
Highly Cited
2001
Highly Cited
2001
Salmonella-based tumor-targeted cancer therapy: tumor amplified protein expression therapy (TAPET) for diagnostic imaging.
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