VHL gene

Known as: VHL, Von Hippel Lindau Tumor Supressor Gene, von Hippel-Lindau tumor suppressor 
This gene is involved in transcriptional repression and protein degradation.
National Institutes of Health

Papers overview

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2015
2015
Foxp3(+) regulatory T (Treg) cells play a critical role in immune homeostasis; however, the mechanisms to maintain their function… (More)
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2012
2012
Aberrant microRNA expression has been implicated in the development of human cancers. Here, we investigated the oncogenic… (More)
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Highly Cited
2005
Highly Cited
2005
The mechanisms by which molecular chaperones assist quality control of cytosolic proteins are poorly understood. Analysis of the… (More)
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Highly Cited
2004
Highly Cited
2004
The ECS (Elongin B/C-Cul2/Cul5-SOCS-box protein) complex is a member of a family of ubiquitin ligases that share a Cullin-Rbx… (More)
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Highly Cited
2004
Highly Cited
2004
Gene expression analysis was performed on a human renal cancer cell line (786-0) with mutated VHL gene and a transfectant with… (More)
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Highly Cited
2003
Highly Cited
2003
Organ-specific metastasis is governed, in part, by interactions between chemokine receptors on cancer cells and matching… (More)
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Highly Cited
2001
Highly Cited
2001
The von Hippel-Lindau tumour suppressor gene product (pVHL) associates with the elongin B and C and Cul2 proteins to form a… (More)
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Highly Cited
2000
Highly Cited
2000
To elucidate the role of somatic alterations for renal cancer etiology and prognosis, we analyzed 227 sporadic renal epithelial… (More)
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1998
1998
It has been shown that an appreciable percentage of patients presenting with primary, apparently sporadic phaeochromocytomas may… (More)
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Highly Cited
1997
Highly Cited
1997
The von Hippel-Lindau tumor suppressor gene (VHL) has a critical role in the pathogenesis of clear-cell renal cell carcinoma (RCC… (More)
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