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VHH Immunoglobulin Fragments
Known as:
VHH Fragments
, Immunoglobulin Fragments, VHH
, Fragments, VHH
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An immunoglobulin fragment composed of one variable domain from an IMMUNOGLOBULIN HEAVY CHAIN from the serum of camelids (ALPACAS, LLAMAS, CAMELS…
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National Institutes of Health
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Broader (1)
Single-Domain Antibodies
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Intracellular displacement of p53 using transactivation domain (p53 TAD) specific nanobodies
Anneleen Steels
,
A. Verhelle
,
O. Zwaenepoel
,
J. Gettemans
mAbs
2018
Corpus ID: 52012541
ABSTRACT The tumor suppressor p53 is of crucial importance in the prevention of cellular transformation. In the presence of…
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2017
2017
A novel photoelectrochemical immunosensor by integration of nanobody and ZnO nanorods for sensitive detection of nucleoside diphosphatase kinase-A.
Anran Liu
,
Kaifei Yin
,
+6 authors
Songqin Liu
Analytica Chimica Acta
2017
Corpus ID: 205221520
2016
2016
Non-Invasive Imaging of Amyloid Deposits in a Mouse Model of AGel Using 99mTc-Modified Nanobodies and SPECT/CT
A. Verhelle
,
Wouter Van Overbeke
,
+6 authors
J. Gettemans
Molecular Imaging and Biology
2016
Corpus ID: 22298124
PurposeGelsolin amyloidosis (AGel), also known as familial amyloidosis, Finnish type (FAF), is an autosomal, dominant, incurable…
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2015
2015
Generation of an alpaca-derived nanobody recognizing γ-H2AX
Malini Rajan
,
O. Mortusewicz
,
+5 authors
M. C. Cardoso
FEBS Open Bio
2015
Corpus ID: 17109839
2014
2014
Interactions between Metal-binding Domains Modulate Intracellular Targeting of Cu(I)-ATPase ATP7B, as Revealed by Nanobody Binding*
Yiping Huang
,
S. Nokhrin
,
+8 authors
S. Lutsenko
Journal of Biological Chemistry
2014
Corpus ID: 32639295
Background: Copper regulates the intracellular localization of a copper transporter ATP7B; the molecular mechanism of this…
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2014
2014
New challenges and opportunities in nonclinical safety testing of biologics.
A. Baumann
,
Kelly M. Flagella
,
+6 authors
Marque D. Todd
Regulatory toxicology and pharmacology : RTP
2014
Corpus ID: 20672235
2014
2014
Affinity capillary electrophoresis to evaluate the complex formation between poliovirus and nanobodies.
H. Halewyck
,
Lise Schotte
,
+4 authors
B. Rombaut
Journal of Separation Science
2014
Corpus ID: 32560639
It was demonstrated that nanobodies with an in vitro neutralizing activity against poliovirus type 1 interact with native virions…
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2013
2013
Anti‐c‐MET Nanobody® – a new potential drug in multiple myeloma treatment
T. Slørdahl
,
T. Denayer
,
+4 authors
T. B. Rø
European Journal of Haematology
2013
Corpus ID: 36239088
c‐MET is the tyrosine kinase receptor of the hepatocyte growth factor (HGF). HGF‐c‐MET signaling is involved in many human…
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Review
2013
Review
2013
Leptin-activity blockers: development and potential use in experimental biology and medicine.
A. Gertler
,
G. Solomon
Canadian Journal of Physiology and Pharmacology
2013
Corpus ID: 27712655
The first adipokine, leptin, discovered almost 20 years ago, is secreted into circulation mainly from adipose tissue and acts…
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Review
2012
Review
2012
Nanobodies as structural probes of protein misfolding and fibril formation.
E. D. De Genst
,
C. Dobson
Methods in molecular biology
2012
Corpus ID: 33169129
The deposition of peptides and proteins as amyloid fibrils is a common feature of nearly 50 medical -disorders affecting the…
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