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VEGFR-2 DNA Vaccine VXM01

Known as: VXM01 
An orally available DNA cancer vaccine containing an attenuated strain of the bacterium Salmonella typhimurium encoding murine vascular endothelial… 
National Institutes of Health

Papers overview

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2019
2019
Імуногістохімічна характеристика маркерів неоангіогенезу у плоскоклітинному раку легені
Цель работы – изучить особенности иммуногистохимической экспрессии VEGFR-2 и CD34… 
2017
2017
VXM01 phase I study in patients with resectable progression of a glioblastoma.
2061Background: VXM01 consists of an attenuated Salmonella typhi Ty21a carrying a plasmid encoding for VEGFR-2. The bacterium is… 
2016
2016
A phase 1 trial extension to assess immunologic efficacy and safety of prime-boost vaccination with VXM01, an oral T cell vaccine against VEGF-receptor 2, in patients with advanced pancreatic cancer.
3091Background: VXM01 is an orally applied tumor vaccine based on live, attenuated salmonella bacteria carrying a eukaryotic… 
2016
2016
Non-clinical safety and antitumor efficacy of live attenuated Salmonella typhimurium-based oral T-cell vaccines VXM01m, VXM04m and VXM06m
2012
2012
Double-blind, placebo-controlled first in human study to investigate an oral vaccine aimed to elicit an immune reaction against the VEGF-Receptor 2 in patients with stage IV and locally advanced…
The investigational oral DNA vaccine VXM01 targets the vascular endothelial growth factor receptor 2 (VEGFR-2) and uses… 
2012
2012
Angiogenic markers in canine lymphoma tissues do not predict survival times in chemotherapy treated dogs.
2008
2008
혈관 내피 성장인자 수용체-2 조절제에 대한 감수성을 판정하기 위한 방법 및 바이오마커
본 발명은 (a) 포유 동물에서 FGF2 농도를 측정하는 단계; 및 (b) 상기 샘플 중의 FGF2 농도를 기준과 비교하여 상기 샘플이 FGF2 양성 부류의 일원인지 FGF2… 
2006
2006
Receptor VEGFR-2 – cel terapii kierowanej w chorobach nowotworowych VEGFR-2 receptor – target for anticancer therapy
wstawania nowych naczyń okołonowotworowych jest naczyniowo-śródbłonkowy czynnik wzrostu VEGF (ang. vascular endothelial growth… 
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