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VAV3 gene

Known as: ONCOGENE VAV3, VAV3, vav guanine nucleotide exchange factor 3 
This gene plays a role in signal transduction and modulation of cell morphology. It is also involved in the regulation of platelet activation.
National Institutes of Health

Related topics

Related topics

3 relations
Cytoskeletal ModelingSignal TransductionVAV3 protein, human

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
The expression profile of genes involved in osteoclastogenesis detected in whole blood of Arabian horses during 3 years of competing at race track.
2017
2017
DNMT3B modulates the expression of cancer-related genes and downregulates the expression of the gene VAV3 via methylation.
Altered promoter DNA methylation is one of the most important epigenetic abnormalities in human cancer. DNMT3B, de novo… 
2016
2016
Inhibition of Vav3 gene can promote apoptosis of human gastric cancer cell line MGC803 by regulating ERK pathway
Previous studies proved that Vav3 gene was overexpressed in cancers. However, the molecular mechanism of Vav3 in apoptosis still… 
2016
2016
VAV3 Gene Polymorphism Is Associated with Paget's Disease of Bone.
BACKGROUND AND AIMS Paget's disease of bone (PDB) is a focal bone disorder affecting the skeleton segmentally. The disease… 
2015
2015
Differential Gene Expression of the Proto-oncogene VAV3 and the Transcript Variant VAV3.1 in Oral Squamous Cell Carcinoma.
The VAV proteins VAV1, VAV2 and VAV3 have been identified as important molecules in tumorigenesis, tumor growth and cell… 
2014
2014
The guanine nucleotide exchange factor Vav3 regulates differentiation of progenitor cells in the developing mouse retina
The seven main cell types in the mammalian retina arise from multipotent retinal progenitor cells, a process that is tightly… 
2008
2008
Targeted overexpression of vav3 oncogene in prostatic epithelium induces nonbacterial prostatitis and prostate cancer.
Our previous study revealed that Vav3 oncogene is overexpressed in human prostate cancer, activates androgen receptor (AR), and… 
2008
2008
Targeted Overexpression of Vav 3 Oncogene in Prostatic Epithelium Induces Nonbacterial Prostatitis and Prostate Cancer
Our previous study revealed that Vav3 oncogene is overexpressed in human prostate cancer, activates androgen receptor (AR), and… 
2002
2002
Adaptor protein APS binds the NH2-terminal autoinhibitory domain of guanine nucleotide exchange factor Vav3 and augments its activity
The N-terminal calponin homology (CH) domain of Vav guanine nucleotide exchange factor is thought to serve a regulatory role in… 
2000
2000
Major transcript variants of VAV3, a new member of the VAV family of guanine nucleotide exchange factors.
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