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Ubiquitin-Activating Enzymes
Known as:
Ubiquitin Activating Enzyme
, Enzyme, Ubiquitin-Activating
, Ubiquitin-Activating Enzymes [Chemical/Ingredient]
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A class of enzymes that catalyzes the ATP-dependent formation of a thioester bond between itself and UBIQUITIN. It then transfers the activated…
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National Institutes of Health
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Related topics
Related topics
12 relations
Narrower (3)
CsdL protein, E coli
UBA2 protein, human
UBA3 protein, human
In Blood
Process of secretion
antagonists & inhibitors
aspects of radiation effects
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Expression of ubiquitin specific peptidase and ATG7 genes in U87 glioma cells upon glutamine deprivation
O. Halkin
,
D. Minchenko
,
О. O. Riabovol
,
V. Telychko
,
О. O. Ratushna
,
O. Minchenko
2017
Corpus ID: 4003301
We have studied the effect of glutamine deprivation on the expression of genes encoding for ubiquitin specific peptidases (usP…
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2014
2014
Conjugation Pathway Mechanistic Study of Uba 5 Enzyme and the Enzymology :
A. Gould
,
Jesse J. Chen
,
+12 authors
K. Hoar
2014
Corpus ID: 207773210
2011
2011
Cellular and biochemical characterization of an inhibitor of the Ubiquitin Activating Enzyme (UAE)
D. Sappal
,
N. Bence
,
+14 authors
J. Bolen
2011
Corpus ID: 86203875
2011
2011
Antitumor activity of ubiquitin activating enzyme (UBA1) inhibitors and use of ubiquitin conjugates as pharmacodynamic biomarkers in human tumor xenografts
J. Huck
,
Tou Liqiang
,
+9 authors
Sai M. Pulukuri
2011
Corpus ID: 83179195
2009
2009
Molecular Pathways Targeting NEDD 8-Activated Cullin-RING Ligases for the Treatment of Cancer
Teresa A. Soucy
,
Peter G. Smith
,
M. Rolfe
2009
Corpus ID: 1310213
E3 ubiquitin ligases regulate many dynamic cellular processes important for cancer cell survival. Together with ubiquitin…
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2008
2008
causes lung cancer growth suppression by targeting cyclin D 1
Qing Feng
,
David J. Sekula
,
+10 authors
E. Dmitrovsky
2008
Corpus ID: 1907538
UBE1L is the E1-like ubiquitin-activating enzyme for the IFN-stimulated gene, 15-kDa protein (ISG15). The UBE1LISG15 pathway was…
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2008
2008
UBE 1 L represses PML / RAR A by targeting the PML domain for ISG 15 ylation
Sumit J. Shah
,
Steven R. Blumen
,
+4 authors
E. Dmitrovsky
2008
Corpus ID: 41251307
Acute promyelocytic leukemia (APL) is characterized by expression of promyelocytic leukemia (PML)/retinoic acid (RA) receptor A…
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2007
2007
Genetic inhibition of the ubiquitin-proteasome pathway : insights into proteasomal targeting
N. Ghaboosi
2007
Corpus ID: 83967662
Regulated proteolysis plays a major role in diverse cellular processes, including cell-cycle progression, endocytosis, apoptosis…
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2005
2005
The Role of Ubiquitin-Mediated Proteolysis of Cyclin D in Breast Cancer
A. Srikanth
2005
Corpus ID: 10022378
Abstract : Cyclin D is a positive regulator of the cell cycle and is found to be highly expressed in breast cancer cells. Cyclin…
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2002
2002
Human Papillomavirus E 6-induced Degradation of E 6 TP 1 Is Mediated by E 6 AP Ubiquitin Ligase 1
Qingshen Gao
,
Ajay Kumar
,
+6 authors
V. Band
2002
Corpus ID: 27149128
High-risk human papilloma viruses are known to be associated with cervical cancers. We have reported previously that the high…
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