USP7 gene

Known as: UBIQUITIN-SPECIFIC PROTEASE 7, UBIQUITIN-SPECIFIC PROTEASE, HERPESVIRUS-ASSOCIATED, ubiquitin specific peptidase 7 (herpes virus-associated) 
This gene is involved in protein deubiquitination.
National Institutes of Health

Papers overview

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Highly Cited
2012
Highly Cited
2012
Transcription-coupled nucleotide-excision repair (TC-NER) is a subpathway of NER that efficiently removes the highly toxic RNA… (More)
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Highly Cited
2012
Highly Cited
2012
The human USP7 deubiquitinating enzyme was shown to regulate many proteins involved in the cell cycle, as well as tumor… (More)
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Review
2011
Review
2011
The deubiquitylating enzyme USP7 (HAUSP) sits at a critical node regulating the activities of numerous proteins broadly… (More)
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Highly Cited
2009
Highly Cited
2009
Pattern recognition receptors represent the first line of defense against invading pathogens. Herpes simplex virus (HSV) encodes… (More)
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Highly Cited
2009
Highly Cited
2009
Deregulation of the ubiquitin/proteasome system has been implicated in the pathogenesis of many human diseases, including cancer… (More)
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Highly Cited
2006
Highly Cited
2006
FOXO (Forkhead box O) transcription factors are important regulators of cellular metabolism, cell-cycle progression and cell… (More)
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Highly Cited
2006
Highly Cited
2006
The ubiquitin-specific protease, USP7, has key roles in the p53 pathway whereby it stabilizes both p53 and MDM2. We show that the… (More)
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Highly Cited
2005
Highly Cited
2005
The packaging of eukaryotic genomic DNA into chromatin is modulated through a range of posttranslational histone modifications… (More)
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Highly Cited
2003
Highly Cited
2003
USP7 or HAUSP is a ubiquitin-specific protease in human cells that regulates the turnover of p53 and is bound by at least two… (More)
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Highly Cited
2003
Highly Cited
2003
The Epstein-Barr nuclear antigen-1 (EBNA1) protein of Epstein-Barr virus is important for the replication, segregation, and… (More)
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