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USP14/UCHL5 Inhibitor VLX1570
Known as:
VLX1570
An inhibitor of the 19S proteasome-specific deubiquitylating enzymes (DUBs) USP14 and UCHL5, with apoptosis-inducing and antineoplastic activities…
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National Institutes of Health
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NCIt Antineoplastic Agent Terminology
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2017
2017
Abstract 3207: Targetting proteasome function by inhibition of the proteasome deubiquitinase USP14
S. Linder
,
Padraig D'arcy
,
Xiaonan Zhang
2017
Corpus ID: 79779654
The 20S proteasome core particle has evolved as an important target for anti-cancer drug development. We previously identified…
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2015
2015
Abstract 4557A: Development of the proteasome deubiquitinase inhibitor VLX1570 for treatment of multiple myeloma
Xin Wang
,
Chitralehka Mohanty
,
+4 authors
S. Linder
2015
Corpus ID: 57470002
Inhibitors of the proteasome-ubiquitin system have been found to be effective in the clinical management of multiple myeloma. We…
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