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USP1 gene

Known as: UBIQUITIN-SPECIFIC PROTEASE 1, USP1, ubiquitin specific peptidase 1 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Abstract 333: USP1 is required for replication fork stability in BRCA1-deficient tumors
Homologous-recombination (HR) deficient tumors with BRCA1 and BRCA2 mutations exhibit replication fork stability defects. To date… 
2017
2017
Identification of deubiquitinase targets of isothiocyanates using SILAC-assisted quantitative mass spectrometry
Cruciferous vegetables such as broccoli and kale have well documented chemopreventative and anticancer effects that are… 
2016
2016
PDGF Engages an E2F-USP1 Signaling Pathway to Support ID2-Mediated Survival of Proneural Glioma Cells.
Glioblastoma is the most aggressive primary brain tumor and responds poorly to currently available therapies. Transcriptomic… 
2016
2016
USP1 Regulates Cellular Senescence by Controlling Genomic Integrity.
2016
2016
Steady-state kinetic studies reveal that the anti-cancer target Ubiquitin-Specific Protease 17 (USP17) is a highly efficient deubiquitinating enzyme.
2016
2016
Title: PDGF Engages an E2F-USP1 Signaling Pathway to Support ID2-mediated Survival of Proneural Glioma Cells Running title: A PDGF-E2F-USP1-ID2 axis is required for proneural glioma
2016
2016
Glioblastoma (GBM) carries a dismal prognosis with a median survival of only a little over a year (1). Current standard of care for patients includes maximal surgical resection followed by radiation…
Transl Cancer Res 2016;5(Suppl 4):S920-S922 tcr.amegroups.com Glioblastoma (GBM) carries a dismal prognosis with a median… 
Review
2014
Review
2014
In vivo genome-wide binding of Id2 to E2F4 target genes as part of a reversible program in mice liver
The inhibitor of differentiation Id2, a protein lacking the basic DNA-binding domain, is involved in the modulation of a number… 
2013
2013
Characterization Of Full-Length, Recombinant Amsh, USP9x, and USP1: Clinically-Relevant Deubiquitinases Involved In Hematological Malignancies
Attachment of polyubiquitin to substrate proteins generates important biological signaling cues that are inherent to the linkage… 
2006
2006
Deubiquitinating PCNA: a downside to DNA damage tolerance
Monoubiquitination of the processivity clamp, PCNA, facilitates the replicative bypass of DNA lesions by recruiting damage… 
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