URATE OXIDASE

Known as: Oxidase, Urate, Uricase, Urate Oxidase [Chemical/Ingredient] 
An enzyme that catalyzes the conversion of urate and unidentified products. It is a copper protein. The initial products decompose to form allantoin… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1937-2018
010203019372017

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2013
2013
Urate is the end product of purine metabolism in humans, owing to the evolutionary disruption of the gene encoding urate oxidase… (More)
Is this relevant?
Highly Cited
2008
Highly Cited
2008
Uric acid is the end product of purine metabolism in humans and great apes, which have lost hepatic uricase activity, leading to… (More)
  • figure 1
  • table 1
  • table 2
  • figure 2
Is this relevant?
Highly Cited
2008
Highly Cited
2008
CONTEXT Hyperuricemia is a predictor for the development of hypertension and is commonly present in new-onset essential… (More)
  • figure 1
  • table 1
  • table 2
  • figure 2
  • table 3
Is this relevant?
Highly Cited
2006
Highly Cited
2006
PEG-modified recombinant mammalian urate oxidase (PEG-uricase) is being developed as a treatment for patients with chronic gout… (More)
  • table 1
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
2002
Highly Cited
2002
We have determined and compared the promoter, coding, and intronic sequences of the urate oxidase (Uox) gene of various primate… (More)
  • figure 1
  • table 1
  • table 2
  • figure 2
  • figure 3
Is this relevant?
Highly Cited
2002
Highly Cited
2002
Urate, a naturally occurring product of purine metabolism, is a scavenger of biological oxidants implicated in numerous disease… (More)
  • figure 1
  • table 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
1994
Highly Cited
1994
Urate oxidase, or uricase (EC 1.7.3.3), is a purine metabolic enzyme that catalyzes the conversion of uric acid to allantoin in… (More)
Is this relevant?
Highly Cited
1992
Highly Cited
1992
Urate oxidase was lost in hominoids during primate evolution. The mechanism and biological reason for this loss remain unknown… (More)
  • figure 1
  • figure 2
  • figure 3
  • table 1
  • figure 4
Is this relevant?
Highly Cited
1989
Highly Cited
1989
Urate oxidase, or uricase (EC 1.7.3.3), is a peroxisomal enzyme that catalyzes the oxidation of uric acid to allantoin in most… (More)
  • figure 1
  • figure 4
  • figure 3
  • table 1
  • figure 5
Is this relevant?
Highly Cited
1980
Highly Cited
1980
A new direct colorimetric procedure for uric acid assay in serum or urine is described, utilizing a 3,5-dichloro-2-hydroxybenzene… (More)
  • figure 1
  • table 2
  • table 3
  • table 4
  • figure 2-4
Is this relevant?