Rasburicase

Known as: Uricase, rasburicase [Chemical/Ingredient], Urate oxidase 
A recombinant urate oxidase enzyme isolated from a genetically-modified strain of Saccharomyces cerevisiae. Urate oxidase catalyzes the oxidation of… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1938-2017
020406019382016

Papers overview

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Highly Cited
2009
Highly Cited
2009
RATIONALE Lung injury leads to pulmonary inflammation and fibrosis through myeloid differentiation primary response gene 88… (More)
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Highly Cited
2008
Highly Cited
2008
Alum (aluminum hydroxide) is the most widely used adjuvant in human vaccines, but the mechanism of its adjuvanticity remains… (More)
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Highly Cited
2005
Highly Cited
2005
BACKGROUND Hyperuricemia has been linked to cardiovascular and renal diseases, possibly through the generation of reactive oxygen… (More)
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Highly Cited
2002
Highly Cited
2002
Hyperuricemia is associated with renal disease, but it is usually considered a marker of renal dysfunction rather than a risk… (More)
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Highly Cited
2002
Highly Cited
2002
Humans have elevated serum uric acid as a result of a mutation in the urate oxidase (uricase) gene that occurred during the… (More)
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Highly Cited
2002
Highly Cited
2002
We have determined and compared the promoter, coding, and intronic sequences of the urate oxidase (Uox) gene of various primate… (More)
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Highly Cited
2002
Highly Cited
2002
A method for rapid morphologic phenotyping is demonstrated by using magnetic resonance microscopy. Whole fixed C57BL/6J mice were… (More)
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Highly Cited
2001
Highly Cited
2001
Standard therapy in the United States for malignancy-associated hyperuricemia consists of hydration, alkalinization, and… (More)
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Highly Cited
1992
Highly Cited
1992
Urate oxidase was lost in hominoids during primate evolution. The mechanism and biological reason for this loss remain unknown… (More)
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Highly Cited
1980
Highly Cited
1980
A new direct colorimetric procedure for uric acid assay in serum or urine is described, utilizing a 3,5-dichloro-2-hydroxybenzene… (More)
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