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UR 12670

Known as: UR-12670 
National Institutes of Health

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2 relations

Broader (2)

ImidazolesPyridines

Papers overview

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2002
2002
Renal ischemia/reperfusion injury in diabetes : experimental studies in the rat.
Diabetes mellitus (DM) is one of the leading causes of end stage renal failure. An increased susceptibility to renal ischemia… 
2001
2001
Protective effect of UR-12670 on chronic nephropathy induced by warm ischaemia in ageing uninephrectomized rats.
BACKGROUND In young animals, renal ischaemia/reperfusion injury and mass reduction are associated with chronic lesions that mimic… 
1997
1997
Effects of a new platelet-activating factor antagonist, UR-12670, on several endotoxic shock markers in rats.
UR-12670 is a novel and potent PAF antagonist, eg., it displaces [3H]WEB-2086 from PAF receptors in rabbit platelet membranes (Ki… 
1996
1996
Design, Synthesis, and Structure−Activity Relationship Studies of Novel 1-[(1-Acyl-4-piperidyl)methyl]-1H-2-methylimidazo[4,5-c]pyridine Derivatives as Potent, Orally Active Platelet−Activating…
Replacement of the polar head of our previous series of 1-acyl-4-[(2-methyl-3-pyridyl)cyanomethyl]piperazines with a 2… 
1996
1996
Characterization of [3H]apafant binding to PAF receptor on rabbit platelet membranes: a comparison of a microplate filtration system and a standard method.
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