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UK 37248

Known as: UK-37,248, UK-37248 
National Institutes of Health

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1 relation

Broader (1)

dazoxiben

Papers overview

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1990
1990
Prostaglandin redirection by thromboxane synthetase inhibition. Attenuation of myocardial stunning in canine heart.
We have previously reported that inhibition of thromboxane synthesis results in an improvement in postischemic function in… 
1988
1988
The role of mediators in the response of the canine peripheral lung to 1 ppm ozone.
We tested the hypothesis that the in vivo response of the canine peripheral lung to 1 ppm ozone is mediated, in part, by… 
1988
1988
Myotropic activity of leukotriene B4 on lung parenchyma strips is not necessarily attributable to thromboxane A2 release.
Leukotriene B4 contracts guinea pig lung parenchymal strips by an indirect mechanism dependent upon formation of myotropic… 
1987
1987
Thromboxane contributes to the immediate antigenic response of canine peripheral airways.
The actions of specific humoral mediators in the immediate response of the canine peripheral airways to antigen challenge are not… 
1983
1983
Effect of the thromboxane synthetase inhibitor UK-37,248 (dazoxiben) upon platelet aggregation, coronary artery thrombosis and vascular reactivity.
The effects of the thromboxane synthetase inhibitor dazoxiben on thrombus formation, platelet aggregation and vascular reactivity… 
Review
1983
Review
1983
Dazoxiben, a thromboxane synthetase inhibitor, in the treatment of Raynaud's syndrome: a double-blind trial.
1 UK-37248 (dazoxiben), an orally active thromboxane synthetase inhibitor, was evaluated in a double-blind trial of patients with… 
Highly Cited
1981
Highly Cited
1981
UK-37, 248, a novel, selective thromboxane synthetase inhibitor with platelet anti-aggregatory and anti-thrombotic activity.
1981
1981
Beneficial effects of a new thromboxane synthetase inhibitor in arachidonate-induced sudden death.
1981
1981
Thromboxane synthetase inhibitors differentially antagonize thromboxane receptors in vascular smooth muscle
SummaryA number of thromboxane (Tx) synthetase inhibitors have been found to prevent thromboxane release in acute cardiopulmonary… 
1981
1981
UK-37,248, A Novel, Selective Thromboxane Synthetase Inhibitor With Anti-Aggregatory And Anti-Thrombotic Activity
UK-37,248, 4-(2-(lH-imidazol-l-yl)ethoxy)benzoic acid hydrochloride, potently inhibited human blood platelet microsomal… 
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