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UGCG gene

Known as: CERAMIDE GLUCOSYLTRANSFERASE, UDP-Glucose Ceramide Glucosyltransferase Gene, GLUCOSYLCERAMIDE SYNTHASE 
This gene is involved in glucosylceramide synthesis.
National Institutes of Health

Related topics

Related topics

5 relations
Ceramide Glucosyltransferase, humanCeramide glucosyltransferaseLipid MetabolismUGCG wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2015
2015
AMP-activated Protein Kinase Suppresses Biosynthesis of Glucosylceramide by Reducing Intracellular Sugar Nucleotides*
Background: Abnormal accumulation of glucosylceramide (GlcCer), a fundamental membranous glycolipid, causes numerous diseases… 
2012
2012
Discovery and characterization of an inhibitor of glucosylceramide synthase.
Targeting glycosphingolipid synthesis has emerged as a novel approach for treating metabolic diseases. 32 (EXEL-0346) represents… 
2012
2012
DNA damage induces down-regulation of UDP-glucose ceramide glucosyltransferase, increases ceramide levels and triggers apoptosis in p53-deficient cancer cells.
2007
2007
Functional gene clustering via gene annotation sentences, MeSH and GO keywords from biomedical literature
Gene function annotation remains a key challenge in modern biology. This is especially true for high-throughput techniques such… 
2003
2003
The absence of functional glucosylceramide synthase does not sensitize melanoma cells for anticancer drugs
Conversion of ceramide, a putative mediator of anticancer drug‐induced apoptosis, into glucosylceramide, by the action of… 
Highly Cited
1999
Highly Cited
1999
Variant effects of non-native kissing-loop hairpin palindromes on HIV replication and HIV RNA dimerization: role of stem-loop B in HIV replication and HIV RNA dimerization.
The genome of all retroviruses consists of two identical RNAs noncovalently linked near their 5' end. In vitro synthesized RNAs… 
1998
1998
Molecular cloning and characterization of the mouse ceramide glucosyltransferase gene.
Ceramide glucosyltransferase (glucosylceramide synthase, GlcT-1, EC 2.4.1.80) catalyzes the first step in glycosphingolipid… 
1998
1998
Structural features of the UCCG and UGCG tetraloops in very short hairpins as evidenced by optical spectroscopy.
Structures of the UCCG and UGCG tetraloops formed in octamer ribonucleotidic hairpin sequences, i.e., 5'-r[GC(UCCG)GC]-3' and 5… 
Highly Cited
1996
Highly Cited
1996
Induction of Ceramide Glucosyltransferase Activity in Cultured Human Keratinocytes
Ceramides are the major component of the extracellular lipids that comprise the epidermal permeability barrier. They are derived… 
1995
1995
Enzymatic formation of plant cerebroside: properties of UDP-glucose: ceramide glucosyltransferase in radish seedlings.
The activity of cerebroside synthase (UDP-glucose: ceramide glucosyltransferase) was found in the microsomal fraction of radish… 
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