UGCG gene

Known as: CERAMIDE GLUCOSYLTRANSFERASE, UDP-Glucose Ceramide Glucosyltransferase Gene, GLUCOSYLCERAMIDE SYNTHASE 
This gene is involved in glucosylceramide synthesis.
National Institutes of Health

Papers overview

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2014
2014
Glycosylation of cellular proteins has important impact on their stability and functional properties, and glycan structures… (More)
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2012
2012
Synthesis inhibition is the basis for the treatment of type 1 Gaucher disease by the glucosylceramide synthase (GCS) inhibitor… (More)
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2011
2011
Inactivation of glycogen synthase kinase (GSK)-3 has been implicated in cancer progression. Previously, we showed an abundance of… (More)
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Highly Cited
2005
Highly Cited
2005
Overexpression of glucosylceramide synthase (GCS), a pivotal enzyme in glycolipid biosynthesis, contributes to cancer cell… (More)
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2005
2005
OBJECTIVE Ceramide, an intermediate of apoptosis induction in response to chemotherapy, can be detoxified by glycosylation at the… (More)
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2004
2004
Ceramide is a key mediator of apoptosis, and is involved in the cellular stress response. We examined the alterations in the… (More)
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2004
2004
Treatment with doxorubicin (DOX) induced apoptosis with an increase of ceramide content in drug-sensitive HL-60 cells, but not in… (More)
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Highly Cited
2000
Highly Cited
2000
Previous work from our laboratory demonstrated that increased competence to glycosylate ceramide conferred adriamycin resistance… (More)
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1999
1999
The genome of all retroviruses consists of two identical RNAs noncovalently linked near their 5' end. In vitro synthesized RNAs… (More)
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1996
1996
Ceramides are the major component of the extracellular lipids that comprise the epidermal permeability barrier. They are derived… (More)
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