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Ceramide Glucosyltransferase, human

Known as: EC 2.4.1.80, Glucosylceramide Synthase, UDP-Glucose:N-Acylsphingosine D-Glucosyltransferase 
Ceramide glucosyltransferase (394 aa, ~45 kDa) is encoded by the human UGCG gene. This protein is involved in the glycosylation of N-acylsphingosine.

Topic mentions per year

Topic mentions per year

1981-2017
02419812017

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9 relations
Carbohydrate MetabolismEnzyme GeneGlycosyltransferase GeneLipid Metabolism
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Broader (1)

Ceramide glucosyltransferase

Related mentions per year

Related mentions per year

1936-2018
19401960198020002020
Ceramide Glucosyltransferase, human
Lipid Metabolism
Carbohydrate Metabolism
Transmembrane Domain
glycosylation
Enzyme Gene

Papers overview

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2011
2011
Ceramide glucosyltransferase of the nematode Caenorhabditis elegans is involved in oocyte formation and in early embryonic cell division.
Ceramide glucosyltransferase (Ugcg) [uridine diphosphate (UDP)-glucose:N-acylsphingosine D-glucosyltransferase or UDP-glucose… (More)
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2008
2008
Glucosylceramide synthase decrease in frontal cortex of Alzheimer brain correlates with abnormal increase in endogenous ceramides: consequences to morphology and viability on enzyme suppression in…
Abnormal increase in native long-chain ceramides (lcCer) in AD implicates roles in neuronal atrophy and cognitive dysfunction… (More)
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2005
2005
Processive lipid galactosyl/glucosyltransferases from Agrobacterium tumefaciens and Mesorhizobium loti display multiple specificities.
The glycosyltransferase family 21 (GT21) includes both enzymes of eukaryotic and prokaryotic organisms. Many of the eukaryotic… (More)
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1998
1998
Molecular cloning and characterization of the mouse ceramide glucosyltransferase gene.
Ceramide glucosyltransferase (glucosylceramide synthase, GlcT-1, EC 2.4.1.80) catalyzes the first step in glycosphingolipid… (More)
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1998
1998
Molecular cloning and expression of mouse ceramide glucosyltransferase.
Ceramide glucosyltransferase (EC 2.4.1.80) catalyzes the first glycosylation step of glycosphingolipid (GSL) synthesis, the… (More)
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1998
1998
Effect of an inhibitor of glucosylceramide synthesis on cultured human keratinocytes.
Glucosylceramide (GlcCer) is a major glycosphingolipid component of epidermis, which is thought to be related to the barrier… (More)
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Highly Cited
1996
Highly Cited
1996
Expression cloning of a cDNA for human ceramide glucosyltransferase that catalyzes the first glycosylation step of glycosphingolipid synthesis.
We have isolated a cDNA encoding human ceramide glucosyltransferase (glucosylceramide synthase, UDP-glucose:N-acylsphingosine D… (More)
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1996
1996
Purification and characterization of UDP-glucose:ceramide glucosyltransferase from rat liver Golgi membranes.
We present a method for solubilizing and purifying UDP-Glc:ceramide glucosyltransferase (EC 2.4.1.80; glucosylceramide synthase… (More)
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Highly Cited
1994
Highly Cited
1994
A mouse B16 melanoma mutant deficient in glycolipids.
Mouse B16 melanoma cell line, GM-95 (formerly designated as MEC-4), deficient in sialyllactosylceramide was examined for its… (More)
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1982
1982
Developmental changes in glycolipid synthesizing enzymes in the brain of a myelin-deficient mutant Wistar rat.
Changes in the activities of UDP-galactose:ceramide galactosyltransferase (CGalT, EC 2.4.1.45), UDP-glucose:ceramide… (More)
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