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UFP 112

Known as: UFP-112, UFP112 
National Institutes of Health

Papers overview

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2015
2015
Severe pain occurs in the context of many diseases and conditions and is a leading cause of disability. Nociceptin/orphanin FQ (N… Expand
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2015
2015
Oxaliplatin and paclitaxel are considered central components in the treatment of colorectal and breast cancer, respectively. The… Expand
2013
2013
Several studies suggest that the N/OFQ (nociceptin/orphanin FQ)-NOP (N/OFQ peptide) receptor pathway is involved in airway… Expand
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Review
2011
Review
2011
Nociceptin/orphanin FQ (N/OFQ) controls several biological functions via selective activation of the N/OFQ peptide receptor (NOP… Expand
Highly Cited
2010
Highly Cited
2010
&NA; Chemical modifications of nociceptin/orphanin FQ (N/OFQ) peptide that result in increased potency and resistance to… Expand
Highly Cited
2007
Highly Cited
2007
[(pF)Phe(4)Aib(7)Arg(14)Lys(15)]N/OFQ-NH(2) (UFP-112) has been designed as a novel ligand for the nociceptin/orphanin FQ (N/OFQ… Expand
2007
2007
Nociceptin/orphanin FQ (N/OFQ), the endogenous NOP receptor ligand, centrally modulates gastric motor and secretory functions and… Expand
2007
2007
Previous structure-activity and NMR studies on nociceptin/orphanin FQ (N/OFQ) demonstrated that Aib substitution of Ala(7) and/or… Expand
2007
2007
The influence of peripheral nociceptin/orphanin FQ (N/OFQ) on cold restraint-induced gastric mucosal damage in the rat was… Expand
Highly Cited
2006
Highly Cited
2006
Activation of the NOP receptor by the endogenous ligand nociceptin/orphanin FQ (N/OFQ) reduces alcohol consumption in genetically… Expand