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UCP1 gene

Known as: UCP1, UNCOUPLING PROTEIN 1, uncoupling protein 1 (mitochondrial, proton carrier) 
This gene plays a role in proton transport.
National Institutes of Health

Related topics

Related topics

7 relations
Cell RespirationHomo sapiensIonophore activityLigand Binding

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2007
Highly Cited
2007
Upconversion fluorescence enables homogeneous immunoassay in whole blood.
Many medical conditions are related to alterations in protein or hormone concentrations in blood. These changes are commonly… 
Highly Cited
2003
Highly Cited
2003
Effects of uncoupling protein 1 and beta3-adrenergic receptor gene polymorphisms on body size and serum lipid concentrations in Japanese women.
Highly Cited
2002
Highly Cited
2002
Chronic central leptin infusion restores hyperglycemia independent of food intake and insulin level in streptozotocin‐induced diabetic rats
We examined the effects of chronic centrally administered leptin on the glucose metabolism of streptozotocin‐induced diabetic… 
Highly Cited
2001
Highly Cited
2001
BMCP1: a mitochondrial uncoupling protein in neurons which regulates mitochondrial function and oxidant production
Outside the nervous system, members of the mitochondrial uncoupling protein (UCP) family have been proposed to contribute to… 
Review
2001
Review
2001
Genetic and physiological analysis of the role of uncoupling proteins in human energy homeostasis
Abstract. The metabolic utilization of substrates results in ATP synthesis and energy loss as heat. In tissues and cells the… 
Highly Cited
2001
Highly Cited
2001
Insulin and contraction directly stimulate UCP2 and UCP3 mRNA expression in rat skeletal muscle in vitro.
To study the regulation of the mitochondrial uncoupling protein 2 and 3 (UCP2 and UCP3), we studied the effect of insulin and… 
Highly Cited
1999
Highly Cited
1999
Regulation of UCP3 by nucleotides is different from regulation of UCP1
Highly Cited
1995
Highly Cited
1995
Functional assessment of white and brown adipocyte development and energy metabolism in cell culture. Dissociation of terminal differentiation and thermogenesis in brown adipocytes.
We investigated the effect of insulin, triiodothyronine (T3) and dexamethasone (a synthetic glucocorticoid) on differentiation… 
Highly Cited
1989
Highly Cited
1989
The uncoupling protein dimer can form a disulfide cross-link between the mobile C-terminal SH groups.
Isolated uncoupling protein (UCP) can be cross-linked, by various disulfide-forming reagents, to dimers. The best cross-linking… 
Highly Cited
1988
Highly Cited
1988
Full expression of uncoupling protein gene requires the concurrence of norepinephrine and triiodothyronine.
We have examined the uncoupling (UCP) protein gene expression in euthyroid and hypothyroid rats. UCP mRNA levels were estimated… 
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