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UCK1 gene
Known as:
FLJ12255
, UCK1
, URIDINE/CYTIDINE KINASE 1
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National Institutes of Health
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Related topics
Related topics
1 relation
UCK2 gene
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
The Cytidine Analog Fluorocyclopentenylcytosine (RX-3117) Is Activated by Uridine-Cytidine Kinase 2
Dzjemma Sarkisjan
,
Joris R. Julsing
,
+6 authors
G. Peters
PloS one
2016
Corpus ID: 15145710
Fluorocyclopentenylcytosine (RX-3117) is an orally available cytidine analog, currently in Phase I clinical trial. RX-3117 has…
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2016
2016
The pivotal role of uridine-cytidine kinases in pyrimidine metabolism and activation of cytotoxic nucleoside analogues in neuroblastoma.
A. V. van Kuilenburg
,
Rutger J. Meinsma
Biochimica et biophysica acta
2016
Corpus ID: 30976247
2016
2016
Purification, activity, and expression levels of two uridine-cytidine kinase isoforms in neuroblastoma cell lines
R. Meinsma
,
A. V. van Kuilenburg
Nucleosides, nucleotides & nucleic acids
2016
Corpus ID: 13436615
ABSTRACT Uridine-cytidine kinase (UCK) catalyzes the phosphorylation of uridine, cytidine, and several pyrimidine ribonucleoside…
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2015
2015
Abstract 2622: Fluorocyclopentenylcytosine (RX-3117) is activated by uridine-cytidine kinase 2, a potential biomarker
G. Peters
,
Joris R. Julsing
,
+5 authors
Deog Joong Kim
2015
Corpus ID: 79105061
Fluorocyclopentenylcytosine (RX-3117) is an orally bioavailable novel cytidine analog, currently being tested in a Phase I…
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Highly Cited
2014
Highly Cited
2014
Expression of nucleoside-metabolizing enzymes in myelodysplastic syndromes and modulation of response to azacitidine
A. Valencia
,
E. Masala
,
+12 authors
V. Santini
Leukemia
2014
Corpus ID: 17666755
The nucleoside analog azacitidine (AZA) is used in the treatment of myelodysplastic syndromes (MDS), but 30–40% of patients fail…
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2010
2010
Comprehensive Mapping of the Human Kinome to Epidermal Growth Factor Receptor Signaling*
K. Komurov
,
D. Padrón
,
Tzuling Cheng
,
M. Roth
,
K. Rosenblatt
,
M. White
The Journal of Biological Chemistry
2010
Corpus ID: 25659913
Disregulation of epidermal growth factor receptor (EGFR) signaling directly promotes bypass of proliferation and survival…
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2004
2004
A CRUCIAL ROLE OF URIDINE/CYTIDINE KINASE 2 IN ANTITUMOR ACTIVITY OF 3′-ETHYNYL NUCLEOSIDES
Daigo Murata
,
Y. Endo
,
+5 authors
Takuma Sasaki
Drug Metabolism and Disposition
2004
Corpus ID: 26650853
The antitumor 3′-ethynyl nucleosides, 1-(3-C-ethynyl-β-d-ribopentofuranosyl)cytosine (ECyd) and 1-(3-C-ethynyl-β-d…
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2003
2003
A Sensitive and Inexpensive Yeast Bioassay for the Mycotoxin Zearalenone and Other Compounds with Estrogenic Activity
R. Mitterbauer
,
H. Weindorfer
,
+5 authors
G. Adam
Applied and Environmental Microbiology
2003
Corpus ID: 45249453
ABSTRACT Zearalenone (ZON) is a nonsteroidal estrogenic mycotoxin produced by plant-pathogenic species of Fusarium. As a…
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Highly Cited
2002
Highly Cited
2002
Sensitivity of Human Cancer Cells to the New Anticancer Ribo‐nucleoside TAS–106 Is Correlated with Expression of Uridine‐cytidine Kinase 2
Y. Shimamoto
,
K. Koizumi
,
+6 authors
M. Fukushima
Japanese journal of cancer research : Gann
2002
Corpus ID: 13705609
TAS–106 [l–(3–C‐ethynyl‐β‐d‐ribo‐pentofuranosyl)cytosine] is a new anticancer ribo‐nucleoside with promising antitumor activity…
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Highly Cited
2001
Highly Cited
2001
Phosphorylation of uridine and cytidine nucleoside analogs by two human uridine-cytidine kinases.
A. V. Van Rompay
,
A. Norda
,
K. Lindén
,
M. Johansson
,
A. Karlsson
Molecular pharmacology
2001
Corpus ID: 9290273
Uridine-cytidine kinases (UCK) have important roles for the phosphorylation of nucleoside analogs that are being investigated for…
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