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UBQLN2 gene

Known as: N4BP4, PLIC2, MOUSE, HOMOLOG OF, CHAP1/DSK2 
This gene may play a role in protein turnover.
National Institutes of Health

Related topics

Related topics

4 relations
Protein Degradation InhibitionUBQLN1 geneUbiquilin-2

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UBQLN2 wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
p62/Sequestosome 1 levels increase and phosphorylation is altered in Cx50D47A lenses, but deletion of p62/sequestosome 1 does not improve transparency
Purpose p62/Sequestosome 1 (p62) is a stress-induced protein that is involved in several different intracellular pathways… 
2018
2018
Chemical shifts of UBQLN2 residues 450-624
2016
2016
Ubiquilin2 as a novel marker for detection of urothelial carcinoma cells in urine
Ubiquilin 2 (UBQLN2), an ubiquitin‐related protein, is strongly expressed in urothelial carcinoma cells, in contrast to no or… 
Review
2016
Review
2016
Genotype-phenotype correlations of amyotrophic lateral sclerosis
Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disease characterized by progressive neuronal loss and… 
2015
2015
Evaluation of Skin Fibroblasts from Amyotrophic Lateral Sclerosis Patients for the Rapid Study of Pathological Features
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disorder characterised by the progressive degeneration of brain… 
2013
2013
Ubiquilin 2 Is Not Associated with Tau Pathology
Accumulation of aberrant proteins in inclusion bodies is a hallmark of many neurodegenerative diseases. Impairment of proteolytic… 
2013
2013
Impaired Activity of the Ubiquitin–Proteasome System in Transgenic Mice Expressing ALS/Dementia-Linked Mutant UBQLN2 (P02.170)
OBJECTIVE: To further explore the pathogenic mechanism of UBQLN2-mediated ALS and ALS/dementia and the effect of mutant UBQLN2 on… 
2012
2012
Amyotrophic lateral sclerosis, frontotemporal lobar dementia, and p62
Amyotrophic lateral sclerosis (ALS) is a familial disease in 10% of cases and is sporadic in 90%; investigations prior to the… 
2012
2012
Mutant UBQLN2 Transgenic Mice Recapitulate Behavioral, Pathological and Neurophysiological Characteristics of Human Ubiqulinopathy (P05.165)
1994
1994
Comparison of rat LIC 53 / 55 deduced amino acid sequence with the sequences of bovine LIC peptides
Cytoplasmic dynein is a multi-subunit complex involved in retrograde organelle transport and some aspects of mitosis. In previous… 
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