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UBE2G2 gene

Known as: UBC7, UBC7, S. CEREVISIAE, HOMOLOG OF, UBIQUITIN-CONJUGATING ENZYME E2G 2 
 
National Institutes of Health

Related topics

Related topics

1 relation
UBE2G1 gene

Papers overview

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2017
2017
Conformational Dynamics and Allostery in E2:E3 Interactions Drive Ubiquitination: gp78 and Ube2g2.
Conformational dynamics plays a fundamental role in molecular recognition and activity in enzymes. The ubiquitin-conjugating… Expand
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Review
2016
Review
2016
Structural insights into the activity and regulation of E 3 ubiquitin ligases
Covalent attachment of one or more ubiquitin molecules to protein substrates governs numerous eukaryotic cellular processes… Expand
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2015
2015
Nonspecific yet decisive: Ubiquitination can affect the native-state dynamics of the modified protein.
Ubiquitination is one of the most common post-translational modifications of proteins, and mediates regulated protein degradation… Expand
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Highly Cited
2014
Highly Cited
2014
Exome sequencing reveals novel and recurrent mutations with clinical impact in blastic plasmacytoid dendritic cell neoplasm
Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a very rare disease that currently lacks genomic and genetic biomarkers… Expand
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Highly Cited
2011
Highly Cited
2011
Dual Role of Ancient Ubiquitous Protein 1 (AUP1) in Lipid Droplet Accumulation and Endoplasmic Reticulum (ER) Protein Quality Control
Quality control of endoplasmic reticulum proteins involves the identification and engagement of misfolded proteins, dislocation… Expand
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2011
2011
Selective ubiquitylation of p21 and Cdt1 by UBCH8 and UBE2G ubiquitin-conjugating enzymes via the CRL4Cdt2 ubiquitin ligase complex.
CRL4(Cdt2) is a cullin-based E3 ubiquitin ligase that promotes the ubiquitin-dependent proteolysis of various substrates… Expand
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2010
2010
Tetra-glutamic acid residues adjacent to Lys248 in HMG-CoA reductase are critical for the ubiquitination mediated by gp78 and UBE2G2.
Sterol-regulated degradation of 3-hydroxy-3-methylglutaryl coenzyme A reductase (HMGCR) is a rapid feedback regulatory mechanism… Expand
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Highly Cited
2007
Highly Cited
2007
Autoregulation of an E2 enzyme by ubiquitin-chain assembly on its catalytic residue
Cells have quality-control mechanisms to recognize non-native protein structures and either help the proteins fold or promote… Expand
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2006
2006
Structure of human ubiquitin-conjugating enzyme E2 G2 (UBE2G2/UBC7).
The human ubiquitin-conjugating enzyme E2 G2 (UBE2G2/UBC7) is involved in protein degradation, including a process known as… Expand
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1998
1998
Identification, expression, and chromosomal localization of ubiquitin conjugating enzyme 7 (UBE2G2), a human homologue of the Saccharomyces cerevisiae ubc7 gene.
Protein degradation is an essential mechanism for the maintenance of cellular homeostasis, in which excess or aberrant proteins… Expand
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