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UBE2G2 gene

Known as: UBC7, UBC7, S. CEREVISIAE, HOMOLOG OF, UBIQUITIN-CONJUGATING ENZYME E2G 2 
National Institutes of Health

Related topics

Related topics

1 relation
UBE2G1 gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Conformational Dynamics and Allostery in E2:E3 Interactions Drive Ubiquitination: gp78 and Ube2g2.
Review
2016
Review
2016
Structural insights into the activity and regulation of E 3 ubiquitin ligases
Covalent attachment of one or more ubiquitin molecules to protein substrates governs numerous eukaryotic cellular processes… 
2016
2016
Pro-inflammatory cytokines enhance ERAD and ATF6α pathway activity in salivary glands of Sjögren's syndrome patients.
Highly Cited
2014
Highly Cited
2014
Exome sequencing reveals novel and recurrent mutations with clinical impact in blastic plasmacytoid dendritic cell neoplasm
Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a very rare disease that currently lacks genomic and genetic biomarkers… 
Highly Cited
2011
Highly Cited
2011
Dual Role of Ancient Ubiquitous Protein 1 (AUP1) in Lipid Droplet Accumulation and Endoplasmic Reticulum (ER) Protein Quality Control
Quality control of endoplasmic reticulum proteins involves the identification and engagement of misfolded proteins, dislocation… 
2011
2011
Selective Ubiquitylation of p21 and Cdt1 by UBCH8 and UBE2G Ubiquitin-Conjugating Enzymes via the CRL4Cdt2 Ubiquitin Ligase Complex
ABSTRACT CRL4Cdt2 is a cullin-based E3 ubiquitin ligase that promotes the ubiquitin-dependent proteolysis of various substrates… 
2010
2010
Tetra-glutamic acid residues adjacent to Lys248 in HMG-CoA reductase are critical for the ubiquitination mediated by gp78 and UBE2G2.
Sterol-regulated degradation of 3-hydroxy-3-methylglutaryl coenzyme A reductase (HMGCR) is a rapid feedback regulatory mechanism… 
Highly Cited
2007
Highly Cited
2007
Autoregulation of an E2 enzyme by ubiquitin-chain assembly on its catalytic residue
Cells have quality-control mechanisms to recognize non-native protein structures and either help the proteins fold or promote… 
2006
2006
Structure of human ubiquitin-conjugating enzyme E2 G2 (UBE2G2/UBC7).
The human ubiquitin-conjugating enzyme E2 G2 (UBE2G2/UBC7) is involved in protein degradation, including a process known as… 
1998
1998
Identification, expression, and chromosomal localization of ubiquitin conjugating enzyme 7 (UBE2G2), a human homologue of the Saccharomyces cerevisiae ubc7 gene.
Protein degradation is an essential mechanism for the maintenance of cellular homeostasis, in which excess or aberrant proteins… 
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